Hartley L R, Strother N, Arnold P K, Mulligan B
Department of Psychology, Murdoch University, Western Australia.
Physiol Behav. 1989 May;45(5):917-21. doi: 10.1016/0031-9384(89)90215-1.
Sixteen student volunteers were administered placebo and 50 mg of chlorpromazine (CPZ) in tablet form, on separate occasions, two hours before testing. Whilst volunteers related pleasant and unpleasant personal life events, the frequency and intensity of expressions on the left and right sides of the face were rated by independent observers. Subsequently the valence of the narration was also rated. Similar to a previous study facial expressions during negative emotions were expressed more often and intensely in the left face but positive emotions were bilaterally represented. CPZ neutralised the emotion on both sides of the face, irrespective of whether it was positive or negative. However, because negative emotions were almost completely lateralised to the left face the drug's effect on this emotion was most pronounced on this side. Independent ratings of the narration of the life events showed CPZ made them more pleasant. It is suggested that emotional arousal increases the asymmetry of behaviours when these are unilaterally represented or controlled. CPZ may equalize the symmetry of behaviour by reducing emotional arousal rather than by blocking all behaviour.
16名学生志愿者在测试前两小时分别服用了安慰剂和50毫克片剂形式的氯丙嗪（CPZ）。当志愿者讲述愉快和不愉快的个人生活事件时，独立观察者对面部左右两侧表情的频率和强度进行评分。随后，叙述的效价也被评分。与之前的一项研究类似，负面情绪期间的面部表情在左脸出现得更频繁、更强烈，但正面情绪则双侧表现。CPZ使面部两侧的情绪均得到中和，无论其是正面还是负面。然而，由于负面情绪几乎完全偏向于左脸，药物对这种情绪的影响在这一侧最为明显。对生活事件叙述的独立评分显示，CPZ使这些叙述更令人愉快。有人认为，当行为单侧表现或受控制时，情绪唤醒会增加行为的不对称性。CPZ可能通过降低情绪唤醒而非通过阻断所有行为来使行为的对称性均等化。
