LaTrenta G S, McCarthy J G, Breitbart A S, May M, Sissons H A
Institute of Reconstructive Plastic Surgery, New York University Medical Center, NY.
Plast Reconstr Surg. 1989 Oct;84(4):578-88.
The type of fixation (rigid skeletal vs. wire) was assessed against embryologic origin (membranous vs. endochondral) and recipient site (depository vs. resorptive) as variables affecting inlay and onlay bone-graft survival in 20 mature dogs. Wet weight and volume measurements were made at operation and at sacrifice (16 weeks). The results were as follows: (1) Rigid skeletal fixation increased bone-graft volume survival over wire fixation (p less than 0.05). (2) Fixation (i.e., rigid skeletal) and embryologic origin (i.e., membranous) were equal determinants of bone-graft volume survival (p less than 0.001); the recipient site was not significant for onlay bone graft survival. (3) Embryologic origin was the only significant determinant of weight survival (p less than 0.001). (4) Inlay bone grafts demonstrated greater weight and volume survival than onlay bone grafts (p less than 0.05). (5) Histologic and microradiographic studies demonstrated bony union of bone grafts fixed with rigid skeletal fixation, while fibrous union predominated in bone grafts fixed with wire technique.
在20只成年犬中，评估了固定类型（刚性骨骼固定与钢丝固定）与胚胎起源（膜内成骨与软骨内成骨）和受体部位（沉积性与吸收性）作为影响嵌入和覆盖骨移植存活的变量。在手术时和处死时（16周）进行湿重和体积测量。结果如下：（1）刚性骨骼固定比钢丝固定增加了骨移植体积存活率（p<0.05）。（2）固定方式（即刚性骨骼固定）和胚胎起源（即膜内成骨）是骨移植体积存活的同等决定因素（p<0.001）；受体部位对覆盖骨移植存活无显著影响。（3）胚胎起源是重量存活的唯一显著决定因素（p<0.001）。（4）嵌入骨移植比覆盖骨移植表现出更高的重量和体积存活率（p<0.05）。（5）组织学和显微放射学研究表明，刚性骨骼固定的骨移植实现了骨愈合，而钢丝技术固定的骨移植以纤维愈合为主。
