Greiman Stephen E, Kent Michael L, Betts John, Cochell Deborah, Sigler Tiah, Tkach Vasyl V
Department of Biology, University of North Dakota, Grand Forks, ND, 10 Cornell Street, 58202, USA; Department of Biology, Georgia Southern University, Statesboro, GA, 30460, USA.
Department of Microbiology, Oregon State University, 220 Nash Hall, Corvallis, OR, 97331, USA.
Vet Parasitol. 2016 Oct 15;229:107-109. doi: 10.1016/j.vetpar.2016.10.003. Epub 2016 Oct 4.
The trematode Nanophyetus salmincola is known as the carrier of Neorickettsia helminthoeca, an obligate intracellular endosymbiotic bacterium that causes salmon poisoning disease (SPD), a fatal disease of dogs. The bacteria are maintained through the complex life cycle of N. salmincola that involves snails Juga plicifera as the first intermediate host, salmonid fishes as the second intermediate host and fish-eating mammals as definitive hosts. N. salmincola was also found to harbor a second species of Neorickettsia that causes the Elokomin fluke fever disease (EFF) which has clinical signs similar to SPD in bears, but only low grade illness in dogs. The EFF agent has not been sequenced. In this study we identified N. salmincola as the vector of yet additional species of Neorickettsia known as Stellanchasmus falcatu (SF) agent using DNA sequencing.
吸虫微小片形吸虫(Nanophyetus salmincola)是嗜碘放线杆菌(Neorickettsia helminthoeca)的载体,嗜碘放线杆菌是一种专性细胞内共生细菌,可导致犬类致命的鲑鱼中毒病(SPD)。这些细菌通过微小片形吸虫的复杂生命周期得以维持,该生命周期涉及褶纹冠蚌(Juga plicifera)作为第一中间宿主、鲑科鱼类作为第二中间宿主以及食鱼哺乳动物作为终末宿主。还发现微小片形吸虫携带着第二种嗜碘放线杆菌,这种细菌会引发伊洛科明吸虫热疾病(EFF),在熊身上具有与SPD相似的临床症状,但在犬类中只会引起轻度疾病。EFF病原体尚未进行测序。在本研究中,我们通过DNA测序确定微小片形吸虫是另一种名为镰状星隙吸虫(SF)病原体的嗜碘放线杆菌的载体。