Foreyt W J, Gorham J R, Green J S, Leathers C W, LeaMaster B R
J Wildl Dis. 1987 Jul;23(3):412-7. doi: 10.7589/0090-3558-23.3.412.
Clinical salmon poisoning disease (SPD), and survival of Neorickettsia helminthoeca and metacercariae of Nanophyetus salmincola in fish were evaluated experimentally in 12-wk-old coyotes (Canis latrans) to determine the potential of SPD for biological control of coyotes. Coyotes readily ate fish that contained metacercariae and rickettsiae. They developed diarrhea, anorexia and lethargy within 7 days after feeding. Infected coyotes lost 58% of their body weight when compared to uninfected controls. They died or became moribund and were euthanatized within 17 days after feeding. Rickettsiae were present in the macrophages of lymph nodes of all affected coyotes. Clinical disease occurred in coyotes fed fresh fish, but not in coyotes fed fish stored at 4 C for greater than or equal to 30 days or at -20 C for 14 days. Metacercariae in fish were viable after 60 days at 4 C. These trematodes developed in coyotes, but clinical SPD did not occur. This indicated survival of metacercariae, but not rickettsiae. Metacercariae were not viable after 14 days at -20 C.
通过在12周龄的郊狼（犬属）身上进行实验，评估了临床鲑鱼中毒病（SPD）以及鲑居尾孢虫的囊蚴和蠕虫新立克次氏体在鱼体内的存活情况，以确定SPD对郊狼进行生物控制的潜力。郊狼很容易吃下含有囊蚴和立克次氏体的鱼。喂食后7天内，它们出现腹泻、厌食和嗜睡症状。与未感染的对照组相比，受感染的郊狼体重减轻了58%。它们在喂食后17天内死亡或濒死，随后被实施安乐死。在所有受影响的郊狼的淋巴结巨噬细胞中都发现了立克次氏体。喂食新鲜鱼的郊狼出现了临床疾病，但喂食在4℃下储存30天及以上或在-20℃下储存14天的鱼的郊狼没有出现临床疾病。鱼体内的囊蚴在4℃下60天后仍具活力。这些吸虫在郊狼体内发育，但未出现临床SPD。这表明囊蚴存活了下来，但立克次氏体没有。囊蚴在-20℃下14天后不再具有活力。
