Yanes Daniel A, Mosser-Goldfarb Joy L
Division of Dermatology, Department of Pediatrics, Nationwide Children's Hospital, Ohio State University Wexner Medical Center, Columbus, Ohio.
Pediatr Dermatol. 2017 Jan;34(1):e30-e31. doi: 10.1111/pde.13018. Epub 2016 Nov 4.
Hydroxyurea is a medication with many well-described cutaneous side effects, notably the dermatomyositis-like eruption known as hydroxyurea dermopathy. Although systemic lupus erythematosus has been reported with hydroxyurea use, cutaneous lupus has not. We report a novel case of chronic cutaneous lupus induced by hydroxyurea and propose that this is a side effect that is distinct from hydroxyurea dermopathy.
羟基脲是一种有许多已充分描述的皮肤副作用的药物,尤其是被称为羟基脲皮肤病的皮肌炎样皮疹。虽然已有使用羟基脲导致系统性红斑狼疮的报道,但皮肤型红斑狼疮尚未见报道。我们报告了一例由羟基脲诱发的慢性皮肤型红斑狼疮的新病例,并提出这是一种与羟基脲皮肤病不同的副作用。