van den Ingh T S, Hartman E G, Bercovich Z
Department of Veterinary Pathology, Faculty of Veterinary Medicine, State University Utrecht, The Netherlands.
Vet Q. 1989 Jul;11(3):175-82. doi: 10.1080/01652176.1989.9694218.
A Leptospira interrogans serogroup australis serovar lora infection in a stud farm is reported. During three successive years (1984-1986) clinical leptospirosis with a severe often rapid, fatal course was seen in 12 foals. Clinical examination revealed severe respiratory distress, depression and pyrexia. Other symptoms were diarrhea (2), jaundice (1), and an unsteady gait (1). Morphological characteristics of the disease were massive pulmonary haemorrhage and haemorrhagic-thrombotic or extracapillary glomerulonephritis with tubulonephrosis and interstitial oedema. In most foals high or increasing MAT titres to serovar bratislava were found; from one foal Leptospira interrogans serovar lora was isolated. Serological examination of all 56 mares at the farm (August 1986) revealed antibodies to serovar bratislava in 64 per cent of the animals. These findings support the idea that Leptospira interrogans serovar bratislava and closely related strains (in this study serovar lora) may be adapted to and maintained by the horse population.
报道了种马场发生的澳大利亚问号钩端螺旋体血清群洛拉血清型感染。在连续三年(1984 - 1986年)间,12匹幼驹出现了临床钩端螺旋体病,病程严重,通常迅速且致命。临床检查发现严重的呼吸窘迫、抑郁和发热。其他症状包括腹泻(2例)、黄疸(1例)和步态不稳(1例)。该病的形态学特征为大量肺出血以及出血性血栓形成或毛细血管外肾小球肾炎,并伴有肾小管肾病和间质水肿。在大多数幼驹中,发现对布拉迪斯拉发血清型的微量凝集试验(MAT)滴度较高或不断升高;从1匹幼驹中分离出了澳大利亚问号钩端螺旋体洛拉血清型。对该马场所有56匹母马(1986年8月)进行的血清学检查显示,64%的动物存在针对布拉迪斯拉发血清型的抗体。这些发现支持了这样一种观点,即问号钩端螺旋体布拉迪斯拉发血清型及密切相关菌株(本研究中的洛拉血清型)可能适应马群并在其中持续存在。