Shu Pei, Ling Wenwu, Zhu Chenjing, Wang Jianchao, Jiang Chong, Zhang Weiwei, Xiao Yue, Ma Xuelei
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy. No. 17, section 3, Renmin Road South, Chengdu, Sichuan 610041, China.
Hell J Nucl Med. 2016 Sep-Dec;19(3):275-277. doi: 10.1967/s002449910412. Epub 2016 Nov 8.
Testicular natural killer/T-cell lymphoma is a rare aggressive extranodal lymphoma associated with Epstein-Barr virus infection. Time to diagnose is crucial as the disease is rapidly progressive and fatal. Early suspicion is documented by imaging studies and testicular biopsies which are key factors for diagnosing testicular natural killer/T-cell lymphoma. However, no reports have described the results of imaging studies. In this paper, contrast-enhanced ultrasonography (CEUS), fluorine-18-fuorodexoyglucose-positron emission tomography/computed tomography (F-FDG PET/CT) and tumor biopsies were all diagnostic of testicular natural killer/T-cell lymphoma. The CEUS showed a clear hyperenhancement which strongly indicted malignant tumor. In conclusion, in our study, CEUS as a first line easy test, may help physicians to make an early diagnosis of the very rare case of testicular T-lymphoma.
睾丸自然杀伤/T细胞淋巴瘤是一种罕见的侵袭性结外淋巴瘤，与爱泼斯坦-巴尔病毒感染有关。由于该疾病进展迅速且致命，诊断时间至关重要。早期怀疑通过影像学检查和睾丸活检得以证实，这些是诊断睾丸自然杀伤/T细胞淋巴瘤的关键因素。然而，尚无报告描述影像学检查的结果。在本文中，对比增强超声（CEUS）、氟-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-FDG PET/CT）和肿瘤活检均诊断为睾丸自然杀伤/T细胞淋巴瘤。CEUS显示明显的高增强，强烈提示为恶性肿瘤。总之，在我们的研究中，CEUS作为一项一线简易检查，可能有助于医生对极罕见的睾丸T细胞淋巴瘤病例进行早期诊断。
