睡眠环境光照强度为 10 勒克斯时，进行工作记忆任务的 fMRI 脑激活减少。
Decrease in fMRI brain activation during working memory performed after sleeping under 10 lux light.
机构信息
Department of Psychiatry, Gil Medical Center, Gachon University, School of Medicine, Incheon, Korea.
Department of Psychiatry, Korea University College of Medicine, Seoul, Korea.
出版信息
Sci Rep. 2016 Nov 9;6:36731. doi: 10.1038/srep36731.
The aim of this study was to investigate the effect of exposure to dim light at night (dLAN) when sleeping on functional brain activation during a working-memory tasks. We conducted the brain functional magnetic resonance imaging (fMRI) analysis on 20 healthy male subjects. All participants slept in a polysomnography laboratory without light exposure on the first and second nights and under a dim-light condition of either 5 or 10 lux on the third night. The fMRI scanning was conducted during n-back tasks after second and third nights. Statistical parametric maps revealed less activation in the right inferior frontal gyrus (IFG) after exposure to 10-lux light. The brain activity in the right and left IFG areas decreased more during the 2-back task than during the 1- or 0-back task in the 10-lux group. The exposure to 5-lux light had no significant effect on brain activities. The exposure to dLAN might influence the brain function which is related to the cognition.
这项研究的目的是探讨睡眠时夜间（dLAN）暗光暴露对工作记忆任务时大脑功能激活的影响。我们对 20 名健康男性进行了脑功能磁共振成像（fMRI）分析。所有参与者在第一个和第二个晚上都在没有光照的多导睡眠图实验室中睡眠，而在第三个晚上则在 5 或 10 勒克斯的暗光条件下睡眠。在第二个和第三个晚上之后进行 fMRI 扫描，并进行 n-back 任务。统计参数图显示，在暴露于 10 勒克斯光后，右侧下额回（IFG）的激活减少。在 10 勒克斯组中，与 1 或 0 回任务相比，右侧和左侧 IFG 区域的大脑活动在 2 回任务中减少更多。5 勒克斯光的暴露对大脑活动没有显著影响。夜间（dLAN）暗光暴露可能会影响与认知相关的大脑功能。
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