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免疫功能低下患者的肺部浸润。可伸缩堵塞导管及支气管肺泡灌洗的诊断价值。

Pulmonary infiltrates in immunocompromised patients. Diagnostic value of telescoping plugged catheter and bronchoalveolar lavage.

作者信息

Xaubet A, Torres A, Marco F, Puig-De la Bellacasa J, Faus R, Agusti-Vidal A

机构信息

Department of Medicine, (Servei de Pneumologia), Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, Spain.

出版信息

Chest. 1989 Jan;95(1):130-5. doi: 10.1378/chest.95.1.130.

DOI:10.1378/chest.95.1.130
PMID:2783304
Abstract

The usefulness of telescoping plugged catheter (TPC) together with bronchoalveolar lavage (BAL) in the same bronchoscopic act in the diagnosis of pulmonary infiltrates was studied in 113 fiberoptic bronchoscopic examinations performed on 96 immunocompromised patients. The TPC cultures detected pulmonary bacterial infections in 25 (22 percent) cases but showed a high frequency of false positive results (12 microorganisms, 27 percent). Bronchoalveolar lavage had an overall diagnostic yield of 49 percent (53 of 113 cases). Combining TPC and BAL diagnostic values, 78 of 113 pulmonary infiltrates (69 percent) were diagnosed. The results obtained by both techniques allowed us to modify the treatment in 35 (31 percent) cases. Combined, TPC and BAL show a good diagnostic yield in immunocompromised patients with pulmonary infiltrates. Both techniques should be performed as the first approach in the evaluation of these patients, and be done in the same bronchoscopic procedure.

摘要

在对96例免疫功能低下患者进行的113次纤维支气管镜检查中,研究了在同一支气管镜操作中使用套叠式堵塞导管(TPC)联合支气管肺泡灌洗(BAL)诊断肺部浸润的效用。TPC培养在25例(22%)病例中检测到肺部细菌感染,但显示出较高的假阳性结果频率(12种微生物,27%)。支气管肺泡灌洗的总体诊断率为49%(113例中的53例)。结合TPC和BAL的诊断价值,113例肺部浸润中有78例(69%)得到诊断。两种技术获得的结果使我们能够在35例(31%)病例中调整治疗方案。联合使用时,TPC和BAL在免疫功能低下的肺部浸润患者中显示出良好的诊断率。这两种技术都应作为评估这些患者的首选方法,并在同一支气管镜检查过程中进行。

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