Campistol J M, Cases A, Botey A, Revert A
Nephrology Service, Hospital Clinic, Barcelona, Spain.
Nephron. 1989;51(1):103-6. doi: 10.1159/000185252.
A patient on maintenance hemodialysis developed an acute encephalopathy closely related to a rapid increase in serum aluminum levels. Aluminum hydroxide and sucralfate had been given in large amounts for the treatment of a gastrointestinal bleeding episode. The breach of the gastrointestinal barrier to aluminum absorption, the increase in gastric pH caused by cimetidine, and the presence of gastric telangiectasia acting together in a uremic patient could have precipitated the acute aluminum encephalopathy.
一名维持性血液透析患者发生了与血清铝水平迅速升高密切相关的急性脑病。此前为治疗一次胃肠道出血事件给予了大量氢氧化铝和硫糖铝。在一名尿毒症患者中，胃肠道铝吸收屏障的破坏、西咪替丁导致的胃pH值升高以及胃毛细血管扩张共同作用，可能促成了急性铝性脑病的发生。
