Datta Sujata, Muñoz-Largacha Juan A, Li Lei, Zhao Grace Qing, Litle Virginia R
Boston University School of Medicine, 72 East Concord St, Boston, MA, 02118, United States.
Department of Surgery, Division of Thoracic Surgery, United States.
Int J Surg Case Rep. 2016;29:108-112. doi: 10.1016/j.ijscr.2016.10.063. Epub 2016 Oct 29.
The identification of subcutaneous metastatic lesions from primary visceral malignancies has increased over time, probably due to an increase in the awareness of their presentation and an increase in cancer survival times. Although the rate of subcutaneous metastases from breast,lung and colon cancer is more significant, the incidence of subcutaneous metastases from esophageal carcinomas is very low. These metastatic lesions usually present metachronously and may signify advanced disease and poor prognosis. We report three cases with early stage esophageal adenocarcinoma treated with surgery with curative intent presenting with subcutaneous metastases two months, two years and three years after their esophagectomy.
随着时间的推移,原发性内脏恶性肿瘤的皮下转移病灶的识别有所增加,这可能是由于对其表现的认识提高以及癌症生存时间延长所致。尽管乳腺癌、肺癌和结肠癌的皮下转移率更高,但食管癌的皮下转移发生率非常低。这些转移病灶通常异时出现,可能预示疾病进展和预后不良。我们报告了三例早期食管腺癌患者,他们接受了根治性手术治疗,在食管切除术后两个月、两年和三年出现皮下转移。