帕金森病与溶剂：是否存在因果关系？
Parkinson's disease and solvents: Is there a causal link?
作者信息
Reis J, Benbrick E, Bonneterre V, Spencer P S
机构信息
Service de neurologie (Prof. Tranchant), CHU de Strasbourg, club de neurologie et environnement, 67200 Strasbourg, France.
Occupational medicine department, faculté de médecine et de pharmacie, université de Poitiers, CHU, 86073 Poitiers, France.
出版信息
Rev Neurol (Paris). 2016 Dec;172(12):761-765. doi: 10.1016/j.neurol.2016.09.012. Epub 2016 Nov 9.
We report here on chronic neurological impairment in three car painters with constant occupational exposure to organic solvents. All had a clinical presentation of Parkinson's disease and, in all cases, SPECT DaTscan brain imaging, using I-FP-CIT, showed bilateral reduction of tracer uptake in the basal ganglia, evidence of dysfunction at the dopaminergic terminal.
我们在此报告三名长期职业性接触有机溶剂的汽车喷漆工出现慢性神经功能损害的情况。他们均有帕金森病的临床表现，并且在所有病例中，使用I-FP-CIT进行的SPECT DaTscan脑成像显示基底神经节双侧示踪剂摄取减少，这是多巴胺能终末功能障碍的证据。
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