Bazzocchi Alberto, Guglielmi Giuseppe
Department of Diagnostic and Interventional Radiology, The "Rizzoli" Orthopaedic Institute, Bologna, Italy.
Department of Radiology, University of Foggia, Foggia, Italy.
Semin Musculoskelet Radiol. 2016 Sep;20(4):317-329. doi: 10.1055/s-0036-1592435. Epub 2016 Nov 14.
When bone becomes frail due to metabolic disorders, one or more vertebral fractures (VFs) may occur. A vertebral body fracture after minor trauma is a hallmark of osteoporosis. VFs represent a target in clinical practice and are often an endpoint in clinical trials. The health care and economic burden of VFs is huge, and they also significantly increase mortality and morbidity, as well as impairing function and quality of life. VFs are frequently clinically silent, thus imaging plays a role not only after symptoms appear but also in screening. A VF can be detected incidentally during imaging examinations performed for different clinical indications. A rapid look at the spine included in the scanned field may lead to the discovery of a VF, which must be reported because the event may change the management of the patient and prevent further problems, defusing the so-called vertebral fracture cascade. This review article focuses on VF awareness and identification to answer these questions: What is a VF? What is the impact of VFs? How can we detect VF?
当骨骼因代谢紊乱而变得脆弱时，可能会发生一处或多处椎体骨折（VF）。轻微创伤后发生的椎体骨折是骨质疏松症的一个标志。椎体骨折是临床实践中的一个治疗靶点，并且常常是临床试验的一个终点。椎体骨折的医疗保健和经济负担巨大，它们还会显著增加死亡率和发病率，以及损害功能和生活质量。椎体骨折在临床上常常没有症状，因此影像学不仅在出现症状后发挥作用，而且在筛查中也发挥作用。椎体骨折可能在针对不同临床指征进行的影像学检查期间被偶然发现。快速查看扫描视野中包含的脊柱可能会发现椎体骨折，必须报告该情况，因为这一事件可能会改变患者的治疗方案并预防进一步的问题，化解所谓的椎体骨折级联反应。这篇综述文章聚焦于椎体骨折的认识和识别，以回答以下问题：什么是椎体骨折？椎体骨折有什么影响？我们如何检测椎体骨折？
