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将核桃纳入2型糖尿病风险成人的饮食及其饮食模式变化:一项随机对照交叉试验。

Inclusion of walnut in the diets of adults at risk for type 2 diabetes and their dietary pattern changes: a randomized, controlled, cross-over trial.

作者信息

Njike Valentine Yanchou, Yarandi Niloufarsadat, Petraro Paul, Ayettey Rockiy G, Treu Judith A, Katz David L

机构信息

Yale University Prevention Research Center, Derby, Connecticut, USA; Griffin Hospital-Derby, Derby, Connecticut, USA.

Griffin Hospital-Derby , Derby, Connecticut , USA.

出版信息

BMJ Open Diabetes Res Care. 2016 Oct 19;4(1):e000293. doi: 10.1136/bmjdrc-2016-000293. eCollection 2016.

Abstract

BACKGROUND

In our recently published study, including walnuts in the diets of adults with prediabetes led to overall improvement in diet quality. This report adds to those study findings by examining the food groups displaced during walnut inclusion in the diets of those adults with prediabetes.

METHODS

Randomized, controlled, modified Latin square parallel design with 2 treatment arms. The 112 participants (31 men, 81 women) were randomly assigned to a diet with or without dietary counseling to regulate calorie intake in a 1:1 ratio. Within each treatment arm, participants were further randomized to 1 of 2 sequence permutations to receive a walnut-included diet with 56 g (366 kcal) of walnuts per day and a walnut-excluded diet. Participants in the calorie-regulated arm received advice from a dietitian to preserve an isocaloric condition while including walnuts. We analyzed the 12 components of the 2010 Healthy Eating Index to examine dietary pattern changes of study participants.

RESULTS

Seafood and plant protein foods intake significantly increased with walnut inclusion, compared with their exclusion (2.14±2.06 vs -0.49±2.33; p=0.003). The ingestion of healthful fatty acids also significantly increased with walnut inclusion, compared with their exclusion (1.43±4.53 vs -1.76±4.80; p=0.02). Dairy ingestion increased with walnut inclusion in the calorie-regulated phase, compared with walnut inclusion without calorie regulation (1.06±4.42 vs -2.15±3.64; p=0.02).

CONCLUSIONS

Our data suggest that walnut inclusion in the diets of adults at risk for diabetes led to an increase in intake of other healthful foods.

TRIAL REGISTRATION NUMBER

NCT02330848.

摘要

背景

在我们最近发表的研究中,将核桃纳入糖尿病前期成年人的饮食中可使饮食质量得到全面改善。本报告通过研究在糖尿病前期成年人饮食中加入核桃时被替代的食物组,补充了这些研究结果。

方法

采用随机、对照、改良拉丁方平行设计,有2个治疗组。112名参与者(31名男性,81名女性)被随机分配到接受或不接受饮食咨询以调节热量摄入的饮食组,比例为1:1。在每个治疗组中,参与者被进一步随机分配到2种序列排列中的1种,以接受每天含有56克(366千卡)核桃的含核桃饮食和不含核桃的饮食。热量调节组的参与者接受营养师的建议,在加入核桃的同时保持等热量状态。我们分析了2010年健康饮食指数的12个组成部分,以研究研究参与者的饮食模式变化。

结果

与不摄入核桃相比,摄入核桃后海鲜和植物蛋白食物的摄入量显著增加(2.14±2.06对-0.49±2.33;p=0.003)。与不摄入核桃相比,摄入核桃后健康脂肪酸的摄入量也显著增加(1.43±4.53对-1.76±4.80;p=0.02)。与无热量调节的核桃摄入相比,在热量调节阶段,摄入核桃后乳制品摄入量增加(1.06±4.42对-2.15±3.64;p=0.02)。

结论

我们的数据表明,将核桃纳入糖尿病风险成年人的饮食中会导致其他健康食物摄入量增加。

试验注册号

NCT02330848。

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