小鼠细胞毒性T细胞可识别HLA - B27抗原，且不受H - 2限制。 - Suppr

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超能文献

Mouse cytotoxic T cells can recognize HLA-B27 antigen without H-2 restriction.

作者信息

Samaan A, Gillet D, Chopin M, Degos L, Pla M

机构信息

Mouse Immunogenetics, U93 INSERM, Saint Louis Hospital, Paris, France.

出版信息

Immunogenetics. 1989;29(3):210-2. doi: 10.1007/BF00373648.

DOI:10.1007/BF00373648

PMID:2784414

Abstract

摘要

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本文引用的文献

Association with beta 2-microglobulin controls the expression of transfected human class I genes.

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HLA antigens expressed on murine cells are preferentially recognized by murine cytotoxic T cells in the context of the H-2 major histocompatibility complex.

Proc Natl Acad Sci U S A. 1986 Dec;83(24):9699-703. doi: 10.1073/pnas.83.24.9699.

H-2-restricted cytolytic T cells specific for HLA can recognize a synthetic HLA peptide.

Nature. 1986;324(6097):578-9. doi: 10.1038/324578a0.

Crosses of two independently derived transgenic mice demonstrate functional complementation of the genes encoding heavy (HLA-B27) and light (beta 2-microglobulin) chains of HLA class I antigens.

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Synthetic peptides as antigens and competitors in recognition by H-2-restricted cytolytic T cells specific for HLA.

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