Bailey D N, Shaw R F
Department of Pathology, University of California, San Diego Medical Center.
J Forensic Sci. 1989 Mar;34(2):407-22.
Cocaine- and methamphetamine-related homicides and fatal accidental overdoses in San Diego County were studied retrospectively for the 1987 calendar year. Cocaine was involved in 66 cases (39 homicides, 27 accidental overdoses), methamphetamine in 32 cases (23 homicides, 9 accidental overdoses), and a combination of cocaine and methamphetamine in 10 cases (4 homicides, 6 accidental overdoses). The composite for cocaine-related deaths was a 30-year-old black man in whom was also found at least 1 other drug, usually ethanol or morphine. The composite for methamphetamine-related deaths was a 32-year-old Caucasian man who used methamphetamine with at least 1 other drug (usually ethanol). For cases involving both cocaine and methamphetamine, the composite was a 36-year-old Caucasian man in whom was also found at least 1 other drug, usually ethanol, codeine, or morphine. Mean tissue concentrations of cocaine and benzoylecgonine were significantly higher in accidental overdoses than in homicides except for cocaine concentrations in liver, which did not differ significantly between the two groups. For methamphetamine-related deaths there was no significant difference between mean tissue concentrations in accidental overdoses and in homicides. Cocaine or methamphetamine or both were involved in approximately one third of homicides in San Diego County in 1987, and when fatal accidental overdoses were included, cocaine was involved in twice as many cases as methamphetamine.
对1987年日历年圣地亚哥县与可卡因和甲基苯丙胺相关的杀人案及意外过量致死案例进行了回顾性研究。可卡因涉及66起案例(39起杀人案,27起意外过量致死),甲基苯丙胺涉及32起案例(23起杀人案,9起意外过量致死),可卡因和甲基苯丙胺共同涉及10起案例(4起杀人案,6起意外过量致死)。与可卡因相关死亡案例的综合情况是一名30岁的黑人男性,其体内还至少发现了1种其他药物,通常是乙醇或吗啡。与甲基苯丙胺相关死亡案例的综合情况是一名32岁的白人男性,他使用甲基苯丙胺时还至少使用了1种其他药物(通常是乙醇)。对于同时涉及可卡因和甲基苯丙胺的案例,综合情况是一名36岁的白人男性,其体内也至少发现了1种其他药物,通常是乙醇、可待因或吗啡。意外过量致死案例中可卡因和苯甲酰爱康宁的平均组织浓度显著高于杀人案中的浓度,但肝脏中的可卡因浓度在两组之间无显著差异。对于与甲基苯丙胺相关的死亡案例,意外过量致死案例和杀人案的平均组织浓度之间无显著差异。1987年圣地亚哥县约三分之一的杀人案涉及可卡因或甲基苯丙胺或两者,若将意外过量致死案例包括在内,涉及可卡因的案例数量是甲基苯丙胺的两倍。