Yuan Y Q, Zhu L Y, Zeng H H, Zhou R, Chen P
Department of Respiratory Medicine, the Second Xiangya Hospital of Central South University, Changsha 410011, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2016 Nov 12;39(11):866-870. doi: 10.3760/cma.j.issn.1001-0939.2016.11.009.
To analyze the clinical features of one case of spontaneous hemothorax caused by primary pleural chondrosarcoma and therefore to improve the understanding of this disease. The clinical features of a case with primary pleural chondrosarcoma were analyzed retrospectively and the related literatures were reviewed.The literature review was carried out with "primary pleural, chondrosarcoma" in Chinese and English respectively, as the search terms in Wanfang Data, CNKI and PubMed database from January 1980 to October 2015. A total of 6 articales, 1 in Chinese and 5 in English, were reviewed. A 29 year-old male patient was admitted to the hospital because of fever, chest tightness, shortness of breath for 20 days. CT scan of the chest showed a mass near the right posterior fourth rib and right pleural effusion.Routine examination of the pleural effusion confirmed the presence of hemothorax. Thoracotomy was performed and revealed hemothorax in the right thorax, and a mass near the pleural apex. The tumor was removed by surgery and pleural decortication was also performed. Pathology study confirmed the diagnosis of high-differentiated chondrosarcoma. The patient was followed and there was no recurrence until now. A total of 6 case reports were retrieved from Wanfang Data, CNKI and PubMed. Five cases had complete data, including 2 males and 3 females(age from 28 to70), and another (a 78-year old male) without adequate data. Primary pleural chondrosarcoma is a rare disease, and hemothorax as the first manifestation is even rare. It is easily to be misdiagnosed due to nonspecific clinical symptoms.The final diagnosis depends ultimately on pathological biopsy. Thoracotomy is the most effective method for treatment of primary pleural chondrosarcoma.
分析1例原发性胸膜软骨肉瘤所致自发性血胸的临床特征，以提高对该疾病的认识。回顾性分析1例原发性胸膜软骨肉瘤患者的临床特征，并复习相关文献。分别以中文和英文的“原发性胸膜、软骨肉瘤”为检索词，检索1980年1月至2015年10月期间万方数据、中国知网和PubMed数据库。共检索到6篇文献，其中中文1篇，英文5篇。1例29岁男性患者因发热、胸闷、气短20天入院。胸部CT扫描显示右后第四肋骨附近有一肿块及右侧胸腔积液。胸腔积液常规检查证实为血胸。行开胸手术，术中见右侧胸腔血胸，胸膜顶附近有一肿块。手术切除肿瘤并行胸膜剥脱术。病理检查确诊为高分化软骨肉瘤。对患者进行随访，至今无复发。从万方数据、中国知网和PubMed共检索到6例病例报告。5例资料完整，其中男性2例，女性3例（年龄28～70岁），另1例（78岁男性）资料不全。原发性胸膜软骨肉瘤是一种罕见疾病，以血胸为首发表现者更为罕见。因其临床症状不具特异性，易被误诊。最终诊断最终依赖于病理活检。开胸手术是治疗原发性胸膜软骨肉瘤最有效的方法。
