Abbey Ashkan M, Shah Nisha V, Forster Richard K, Suh Leejee H
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Indian J Ophthalmol. 2016 Sep;64(9):674-676. doi: 10.4103/0301-4738.194330.
We report an interesting case of infectious scleritis from coinfection of Pseudomonas aeruginosa and Bipolaris with no corneal infiltrate. A healthy 60-year-old man with a history of infectious scleritis following pterygium excision presented with purulent material growing P. aeruginosa and 1+ colonies of Bipolaris species of fungus. Broad spectrum treatment was initiated with hourly topical moxifloxacin, fortified tobramycin, and natamycin along with a subconjunctival injection of voriconazole and topical cyclosporine, with PO ketoconazole. After 10 weeks of aggressive empiric treatment, the patient's symptoms had resolved, and his vision returned to baseline although a scleral patch graft was utilized to stabilize scleral thinning.
我们报告了一例有趣的感染性巩膜炎病例,该病例由铜绿假单胞菌和双极霉属共同感染引起,无角膜浸润。一名60岁健康男性,有翼状胬肉切除术后感染性巩膜炎病史,其脓性分泌物培养出铜绿假单胞菌及1+菌落的双极霉属真菌。开始采用广谱治疗,每小时局部应用莫西沙星、强化妥布霉素和那他霉素,同时结膜下注射伏立康唑和局部应用环孢素,并口服酮康唑。经过10周的积极经验性治疗,患者症状缓解,视力恢复至基线水平,尽管使用了巩膜补片移植来稳定巩膜变薄。