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晚期肺肉瘤样癌的根治性放化疗

Definitive Chemoradiotherapy for Advanced Pulmonary Sarcomatoid Carcinoma.

作者信息

Takeda Kazuya, Matsushita Haruo, Kubozono Masaki, Tanabe Takaya, Ishikawa Yojiro, Yamamoto Takaya, Kozumi Maiko, Takahashi Noriyoshi, Katagiri Yu, Tasaka Shun, Fukui Katsuya, Takeda Ken, Fujishima Fumiyoshi, Ichinose Masakazu, Jingu Keiichi

机构信息

Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Japan.

出版信息

Intern Med. 2016;55(22):3325-3330. doi: 10.2169/internalmedicine.55.6990. Epub 2016 Nov 15.

Abstract

Pulmonary sarcomatoid carcinoma is a rare subtype of non-small cell lung cancer with a poor prognosis. We herein report on a case of pulmonary sarcomatoid carcinoma that was treated successfully by concurrent chemoradiotherapy. A 65-year-old man was diagnosed to have pulmonary pleomorphic carcinoma (clinical T4N2M0 stage IIIB). He received concurrent chemoradiotherapy (60 Gy of radiotherapy in 30 fractionations and two courses of chemotherapy with carboplatin and paclitaxel). After chemoradiotherapy, a significant reduction of the tumor size was observed. Two courses of adjuvant chemotherapy were performed. He is currently alive at 15 months after the first treatment without any recurrence or metastasis.

摘要

肺肉瘤样癌是一种预后较差的非小细胞肺癌罕见亚型。我们在此报告一例通过同步放化疗成功治疗的肺肉瘤样癌病例。一名65岁男性被诊断为肺多形性癌(临床T4N2M0 IIIB期)。他接受了同步放化疗(30次分割放疗60 Gy以及两疗程卡铂和紫杉醇化疗)。放化疗后,观察到肿瘤大小显著缩小。进行了两疗程辅助化疗。他在首次治疗后15个月仍存活,无任何复发或转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e7ec/5173502/1a00be45e0d9/1349-7235-55-3325-g001.jpg

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