Toescu Sebastian M, Alalade Andrew F, Steele Louise, Bhargava Deepti, Hunter Roger
Victor Horsley Department of Neurosurgery, National Hospital of Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK.
Department of Neurosurgery, Royal London Hospital, Whitechapel Road, London, E1 1BB, UK.
Acta Neurochir (Wien). 2017 Feb;159(2):393-396. doi: 10.1007/s00701-016-3024-9. Epub 2016 Nov 16.
We report the case of a large osteoblastoma arising in the frontal bone of a 20-year-old female. The lesion was first noted after a fall, and grew steadily in size following further head injury during pregnancy. Initial plain radiography demonstrated an area of radiolucency, with subsequent cross-sectional imaging revealing the extent of the lesion. Following successful surgical resection, histological features were suggestive of an aggressive osteoblastoma with aneurysmal bone cyst-like changes. We consider the influence of pregnancy and trauma on osteoblastoma behavior.
我们报告了一例发生于一名20岁女性额骨的巨大骨母细胞瘤病例。该病变在一次跌倒后首次被发现,并在孕期再次头部受伤后尺寸稳步增大。最初的X线平片显示有透亮区,随后的横断面成像揭示了病变范围。成功手术切除后,组织学特征提示为具有动脉瘤样骨囊肿样改变的侵袭性骨母细胞瘤。我们考虑了妊娠和创伤对骨母细胞瘤行为的影响。