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Current perspectives on the antidepressant-like effects of guanosine.

作者信息

Bettio Luis E B, Gil-Mohapel Joana, Rodrigues Ana Lúcia S

机构信息

Department of Biochemistry, Center of Biological Sciences, Federal University of Santa Catarina, Florianópolis-SC, Brazil.

Division of Medical Sciences and UBC Island Medical Program, University of Victoria, Victoria, BC, V8W 2Y2, Canada.

出版信息

Neural Regen Res. 2016 Sep;11(9):1411-1413. doi: 10.4103/1673-5374.191209.

DOI:10.4103/1673-5374.191209
PMID:27857738
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5090837/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/5090837/f196f55d96ca/NRR-11-1411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/5090837/f196f55d96ca/NRR-11-1411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d9/5090837/f196f55d96ca/NRR-11-1411-g001.jpg

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Current perspectives on the antidepressant-like effects of guanosine.鸟苷抗抑郁样作用的当前观点。
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Front Cell Neurosci. 2018 Oct 23;12:376. doi: 10.3389/fncel.2018.00376. eCollection 2018.

本文引用的文献

1
Guanosine and its role in neuropathologies.鸟苷及其在神经病理学中的作用。
Purinergic Signal. 2016 Sep;12(3):411-26. doi: 10.1007/s11302-016-9509-4. Epub 2016 Mar 22.
2
The antidepressant-like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation.长期鸟苷治疗的抗抑郁样作用与海马神经元分化增加有关。
Eur J Neurosci. 2016 Apr;43(8):1006-15. doi: 10.1111/ejn.13172. Epub 2016 Feb 26.
3
Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics.氯胺酮与速效抗抑郁药：开启情绪障碍治疗新神经生物学的一扇窗。
Annu Rev Med. 2015;66:509-23. doi: 10.1146/annurev-med-053013-062946. Epub 2014 Oct 17.
4
Guanosine prevents behavioral alterations in the forced swimming test and hippocampal oxidative damage induced by acute restraint stress.鸟苷可预防急性束缚应激诱导的强迫游泳试验中的行为改变和海马氧化损伤。
Pharmacol Biochem Behav. 2014 Dec;127:7-14. doi: 10.1016/j.pbb.2014.10.002. Epub 2014 Oct 12.
5
Guanosine promotes proliferation of neural stem cells through cAMP-CREB pathway.鸟苷酸通过 cAMP-CREB 通路促进神经干细胞增殖。
J Biol Regul Homeost Agents. 2013 Jul-Sep;27(3):673-80.
6
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.鸟苷通过调节 NMDA 受体、一氧化氮-cGMP 和 PI3K/mTOR 通路产生抗抑郁样作用。
Behav Brain Res. 2012 Oct 1;234(2):137-48. doi: 10.1016/j.bbr.2012.06.021. Epub 2012 Jun 26.
7
Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway.鸟苷酸通过 PI3K/Akt/GSK-3β 通路诱导血红素加氧酶-1 的表达来保护人神经母细胞瘤 SH-SY5Y 细胞免受线粒体氧化应激。
Neurochem Int. 2012 Aug;61(3):397-404. doi: 10.1016/j.neuint.2012.05.021. Epub 2012 Jun 7.
8
Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion.慢性鸟苷处理对慢性大脑低灌注大鼠海马损伤和认知障碍的影响。
Neurol Sci. 2012 Oct;33(5):985-97. doi: 10.1007/s10072-011-0872-1. Epub 2011 Dec 14.
9
Guanosine improves motor behavior, reduces apoptosis, and stimulates neurogenesis in rats with parkinsonism.鸟苷可改善帕金森病大鼠的运动行为、减少细胞凋亡并刺激神经发生。
J Neurosci Res. 2009 Feb 15;87(3):617-25. doi: 10.1002/jnr.21883.
10
Neurotrophic effects of extracellular guanosine.细胞外鸟苷的神经营养作用
Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):666-72. doi: 10.1080/15257770802143913.