Ferreira Karen S, Guilherme Gisela, Faria Viviane R, Borges Larissa M, Uchiyama Angel A T
Headache Clinic, University Hospital of School of Medicine, University of Sao Paulo, Ribeirao Preto, SP, Brazil and Neurology Clinic, School of Medicine, University Center Barão de Mauá, Ribeirão Preto, SP, Brazil.
Neurology Clinic, School of Medicine, University Center Barão de Mauá, Ribeirão Preto, SP, Brazil.
Headache. 2017 Jan;57(1):135-142. doi: 10.1111/head.12969. Epub 2016 Nov 10.
Menstrual migraine is a highly prevalent disorder among adult women, resulting in disability and loss of quality of life. Some studies have reported menstrual cycle synchrony among women living together. No study has reported whether there may also be a higher prevalence of menstrual migraine among these women. Thus, they reported here the prevalence of menstrual migraine in a group of women living together compared with a control group of women living alone, and discussed the possible factors involved.
The study was conducted on female university students aged 18-30 years with a diagnosis of migraine according to the criteria of the International Classification of Headache Disorders III, beta appendix criteria. The subjects were divided into a group of women who lived together with two or more other students and a control group of age-matched students who lived alone, interviewed with a specific questionnaire and assessed for 3 months by means of a paper pain diary. The data evaluated included frequency of headache, presence of menstrual migraine, intensity of headache, medications used including contraceptives, and triggering factors such as diet, sleep deprivation, and stress. The menstrual data and data related to migraine were also investigated in the roommates.
A higher occurrence of menstrual migraine among women living together (9, 50%) compared with women living alone (3, 16.7%) (P = .03) was detected. After binary logistic regression analysis, this finding was not related to the main influencing factors detected, that is, use of a contraceptive, test stress, or sleep deprivation (P = .03, adjusted odds ratio: 7.87; 1.23-50.36). These women also showed menstrual cycle synchrony with their roommates (8, 44.4%) and the presence of headache crises during the menstruation of their colleagues (11, 61.1%).
The present study detected a higher occurrence of menstrual migraine among women who lived together. Since there was no previous description of this topic in the literature, it was believed that the present study could represent a step toward more elaborate investigations of this complex topic.
月经性偏头痛是成年女性中一种高度普遍的疾病，会导致残疾和生活质量下降。一些研究报告了共同生活的女性之间月经周期同步的情况。尚无研究报告这些女性中月经性偏头痛的患病率是否也可能更高。因此，他们在此报告了一组共同生活的女性与一组独居女性对照组中月经性偏头痛的患病率，并讨论了其中可能涉及的因素。
该研究针对年龄在18 - 30岁、根据《国际头痛疾病分类第三版，β附录标准》诊断为偏头痛的女大学生进行。受试者被分为一组与两名或更多其他学生共同生活的女性，以及一组年龄匹配的独居学生对照组，通过特定问卷进行访谈，并通过纸质疼痛日记进行3个月的评估。评估的数据包括头痛频率、月经性偏头痛的存在情况、头痛强度、使用的药物（包括避孕药）以及饮食、睡眠不足和压力等触发因素。还对室友的月经数据和与偏头痛相关的数据进行了调查。
检测发现共同生活的女性中月经性偏头痛的发生率（9例，50%）高于独居女性（3例，16.7%）（P = 0.03）。经过二元逻辑回归分析，这一发现与检测到的主要影响因素无关，即避孕药的使用、考试压力或睡眠不足（P = 0.03，调整后的优势比：7.87；1.23 - 50.36）。这些女性还与室友表现出月经周期同步（8例，44.4%），并且在同事月经期间出现头痛发作（11例，61.1%）。
本研究检测到共同生活的女性中月经性偏头痛的发生率更高。由于此前文献中没有对该主题的描述，因此认为本研究可能是朝着对这一复杂主题进行更深入研究迈出的一步。
