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伴有多发钙化的慢性腮腺炎:临床及唾液腺内镜检查结果

Chronic parotitis with multiple calcifications: Clinical and sialendoscopic findings.

作者信息

Jáuregui Emmanuel, Kiringoda Ruwan, Ryan William R, Eisele David W, Chang Jolie L

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco School of Medicine, San Francisco, California, U.S.A.

Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, U.S.A.

出版信息

Laryngoscope. 2017 Jul;127(7):1565-1570. doi: 10.1002/lary.26386. Epub 2016 Nov 15.

Abstract

OBJECTIVES/HYPOTHESIS: To characterize clinical, imaging, and sialendoscopy findings in patients with chronic parotitis and multiple parotid calcifications.

STUDY DESIGN

Retrospective review.

METHODS

Clinical history, radiographic images and reports, lab tests, and operative reports were reviewed for adult patients with chronic parotitis and multiple parotid calcifications who underwent parotid sialendoscopy.

RESULTS

Thirteen of 133 (10%) patients undergoing parotid sialendoscopy for chronic sialadenitis had more than one calcification in the region of the parotid gland. Seven patients (54%) were diagnosed with immune-mediated disease from autoimmune parotitis (positive Sjögren's antibodies or antinuclear antibodies) or human immunodeficiency virus (HIV) disease. The six patients (46%) who did not have an immune-mediated disorder had most calcifications located anterior or along the masseter muscle. Eight of 13 patients (61%) had at least one calculus found in the parotid duct on sialendoscopy. Four patients (38%) had multiple punctate calcifications within the parotid gland, all of whom had either autoimmune parotitis or HIV. None of the proximal or punctate parotid calcifications posterior to the masseter were visualized on sialendoscopy.

CONCLUSIONS

Chronic parotitis in conjunction with multiple parotid calcifications is uncommon and was identified in 10% of our cohort. We contrast two classifications of parotid calcifications: 1) intraductal stones that cause recurrent duct obstruction and are often located within the main parotid duct along or anterior to the masseter and 2) punctate intraparenchymal parotid gland calcifications that are not visualized on sialendoscopy and may represent underlying inflammatory disease.

LEVEL OF EVIDENCE

4 Laryngoscope, 127:1565-1570, 2017.

摘要

目的/假设:描述慢性腮腺炎和腮腺多发钙化患者的临床、影像学及唾液腺内镜检查结果。

研究设计

回顾性研究。

方法

对接受腮腺唾液腺内镜检查的慢性腮腺炎和腮腺多发钙化成年患者的临床病史、影像学图像及报告、实验室检查结果和手术报告进行回顾。

结果

133例因慢性涎腺炎接受腮腺唾液腺内镜检查的患者中,13例(10%)腮腺区域有不止一处钙化。7例患者(54%)被诊断为自身免疫性腮腺炎(抗干燥综合征抗体或抗核抗体阳性)或人类免疫缺陷病毒(HIV)疾病导致的免疫介导疾病。6例(46%)无免疫介导疾病的患者,其大部分钙化位于腮腺前部或沿咬肌分布。13例患者中有8例(61%)在唾液腺内镜检查时发现腮腺导管内至少有一枚结石。4例患者(38%)腮腺内有多个点状钙化,均患有自身免疫性腮腺炎或HIV。在唾液腺内镜检查中未发现咬肌后方腮腺近端或点状钙化。

结论

慢性腮腺炎合并腮腺多发钙化并不常见,在我们的队列中占10%。我们对比了两种腮腺钙化分类:1)导管内结石,可导致反复导管阻塞,常位于腮腺主导管内,沿咬肌或其前方;2)腮腺实质内点状钙化,在唾液腺内镜检查中不可见,可能代表潜在的炎症性疾病。

证据级别

4 喉镜,127:1565 - 1570,2017年。

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