Suppr超能文献

英国一家三级医疗中心使用Bravo无线食管pH监测系统的两年经验。

Two years' experience of using the Bravo wireless oesophageal pH monitoring system at a single UK tertiary centre.

作者信息

Rao Nagendra M, Campbell David I, Rao Prithviraj

机构信息

Centre for Paediatric Gastroenterology, Hepatology and Nutrition, Sheffield Children's Hospital, Sheffield, UK.

出版信息

Acta Paediatr. 2017 Feb;106(2):312-315. doi: 10.1111/apa.13667. Epub 2016 Dec 6.

Abstract

AIM

The Bravo wireless pH monitoring system enables oesophageal pH to be monitored in children intolerant to nasal catheters and records measurements over 48 hours. This study aimed to document the minimum child weight that enabled successful capsule placement and any associated complications. We also compared the diagnostic sensitivity of 48 hours versus 24 hours.

METHODS

We included 203 consecutive patients (122 male children) with clinically documented or suspected reflux symptoms. The age range was two years to 19 years, and the minimum weight was 9.29 kg. The pH capsule was deployed endoscopically under general anaesthetic. Recordings taken over 24 and 48 hours were compared to determine the frequency of differences and correlations in the reflux index and DeMeester scores.

RESULTS

Testing using the detached probe was successful in 190 children (93.6%) with weight as low as 9.29 kg, with no side effects, with failed deployment being the most frequent problem. Clinically different results in the reflux index were found in 16% of the children's day 1 or day 2 readings (p < 0.0001), suggesting the benefit of 48-hour measurements.

CONCLUSION

Measuring oesophageal pH with the Bravo wireless pH monitoring system was successful in 93.6% of cases. A 48-hour test improved the detection rate of gastro-oesophageal reflux disease by 16%.

摘要

目的

Bravo无线pH监测系统能够对不耐受鼻导管的儿童进行食管pH监测,并记录48小时内的测量值。本研究旨在记录成功放置胶囊的最低儿童体重以及任何相关并发症。我们还比较了48小时与24小时监测的诊断敏感性。

方法

我们纳入了203例连续的患者(122例男童),他们有临床记录的或疑似反流症状。年龄范围为2岁至19岁,最低体重为9.29千克。pH胶囊在全身麻醉下通过内镜放置。比较24小时和48小时的记录,以确定反流指数和DeMeester评分的差异频率及相关性。

结果

190名儿童(93.6%)使用分离探头测试成功,体重低至9.29千克,且无副作用,放置失败是最常见的问题。16%的儿童在第1天或第2天的读数中反流指数出现临床不同结果(p < 0.0001),表明48小时测量的益处。

结论

使用Bravo无线pH监测系统测量食管pH,93.6%的病例获得成功。48小时测试使胃食管反流病的检出率提高了16%。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验