Uspenskiĭ V M, Baranovskiĭ A Iu, Vashchenkov V M
Ter Arkh. 1989;61(2):21-3.
Altogether 138 patients with peptic and mediogastral ulcers were examined for cellular immunity. Long before the disease took an unfavourable course marked by frequent relapses and chronic ulcers or the occurrence of ulcer malignancy the patients showed immunodeficiency which correlated with the gravity of the disease clinical manifestations or with the degree of the symptomatology of a complication. At the same time there was a rise of the suppressor activity of T lymphocytes and a reduction in the D lymphocyte count, especially in the patients with gastric ulcer malignancy. It is concluded that the methods of cellular immunity studies should be introduced in medical practice on a broader scale in order to predict the character of the course and complications of gastric ulcers.
对138例消化性溃疡和胃中部溃疡患者进行了细胞免疫检查。早在疾病呈现以频繁复发、慢性溃疡或溃疡恶变的发生为特征的不利病程之前，患者就已表现出免疫缺陷，这与疾病临床表现的严重程度或并发症的症状学程度相关。同时，T淋巴细胞的抑制活性升高，D淋巴细胞计数减少，尤其是胃溃疡恶变患者。结论是，细胞免疫研究方法应在医学实践中更广泛地应用，以预测胃溃疡的病程特征和并发症。
