新生儿缺氧缺血性脑病（HIE）治疗性低温治疗后的儿童期预后。
Outcomes in childhood following therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy (HIE).
作者信息
Natarajan Girija, Pappas Athina, Shankaran Seetha
机构信息
Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI.
Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI.
出版信息
Semin Perinatol. 2016 Dec;40(8):549-555. doi: 10.1053/j.semperi.2016.09.007. Epub 2016 Nov 15.
Abstract
In this article, we review the childhood outcomes of neonates with birth depression and/or hypoxic-ischemic encephalopathy. The outcomes of these children prior to the era of hypothermia for neuroprotection will first be summarized, followed by discussion of results from randomized controlled trials of therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy. The predictors of outcome in childhood following neonatal HIE using clinical and imaging biomarkers following hypothermia therapy will be described.
摘要
在本文中，我们回顾了患有出生时窒息和/或缺氧缺血性脑病的新生儿的儿童期预后情况。首先将总结在神经保护低温疗法时代之前这些儿童的预后情况，随后讨论新生儿缺氧缺血性脑病治疗性低温疗法的随机对照试验结果。还将描述在低温治疗后使用临床和影像学生物标志物对新生儿缺氧缺血性脑病患儿儿童期预后的预测因素。
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