Rodhouse Christine, Soliman Iman, Cruse Mariah, Kastrenakes Joseph, Augustine C J, Ludy Alexis, Reintgen Eric, Hoadley Alexa, Desai Divya, Nguyen Minh, Reintgen Douglas Scott
Florida Hospital - N Pinellas, University of South Florida, Morsani College of Medicine, Tampa, FL.
Florida Hospital - N Pinellas, University of South Florida, Morsani College of Medicine, Tampa, FL.
Clin Breast Cancer. 2017 Feb;17(1):18-22. doi: 10.1016/j.clbc.2016.10.007. Epub 2016 Oct 19.
With the advent and proliferation of breast cancer screening programs, more women are being diagnosed with mammographic abnormalities that require tissue diagnosis. If imaged-guided biopsy is not possible or previous image-guided biopsies reveal pathologies that require more extensive surgery, guided excisional biopsy/lumpectomy may be necessary.
Fifteen women were enrolled in the study of the feasibility of off-site or day-before wire-localization excisional biopsy of the breast with mammographic abnormalities. Five patients had their localization wire placed the day before, whereas 10 patients had their localization the same day with surgery in a distant procedure room under straight local anesthesia.
Two of the 15 patients had an eventual cancer diagnosis from their wire-localized excisional breast biopsy. All patients had their mammographic abnormality removed with the previously placed core biopsy clip, and there was 100% radiologic/clinical correlation. All patients' wounds healed primarily without any surgical site infections.
The protocol answers 2 questions concerning the wire-localized excisional breast biopsy technique. The series shows that the wire-localization technique can be performed the night before or in a location away from the procedure room that would allow better synchronization with surgical schedules or allow the procedure to take place in low-cost settings away from the expense of the hospital operating room.
随着乳腺癌筛查项目的出现和普及，越来越多的女性被诊断出有需要进行组织诊断的乳房X光检查异常情况。如果无法进行影像引导活检，或者之前的影像引导活检显示需要更广泛手术的病理情况，可能需要进行引导切除活检/乳房肿块切除术。
15名女性参与了关于对乳房X光检查异常进行异地或术前一天钢丝定位切除活检可行性的研究。5名患者在前一天放置定位钢丝，而10名患者在同一天在远处手术室接受直接局部麻醉下手术时进行定位。
15名患者中有2名最终通过钢丝定位切除乳房活检被诊断为癌症。所有患者均通过先前放置的粗针活检夹切除了乳房X光检查异常部位，且影像学/临床相关性达100%。所有患者的伤口均一期愈合，无任何手术部位感染。
该方案回答了关于钢丝定位切除乳房活检技术的两个问题。该系列研究表明，钢丝定位技术可在前一晚进行，或在远离手术室的地点进行，这样可以更好地与手术安排同步进行，或者可以在低成本环境下进行该手术，而无需承担医院手术室的费用。
