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泌乳素瘤与妊娠——包括垂体卒中的一系列病例

Prolactinoma and pregnancy - a series of cases including pituitary apoplexy.

作者信息

Galvão Ana, Gonçalves Daniela, Moreira Marta, Inocêncio Gonçalo, Silva Clara, Braga Jorge

机构信息

a Centro Hospitalar do Porto - Centro Materno Infantil do Norte , Porto , Portugal.

出版信息

J Obstet Gynaecol. 2017 Apr;37(3):284-287. doi: 10.1080/01443615.2016.1233946. Epub 2016 Nov 21.

Abstract

The objective of this article is to evaluate the impact of pregnancy in women with prolactinoma, the possible consequences of therapy maintenance/discontinuation during pregnancy and to assess the type of delivery and maternal-foetal obstetrical outcome. A retrospective study of all pregnant women with prolactinoma in our Centre between 2006 and 2014 was made. We had 35 cases of pregnant women with prolactinoma, two of which had an episode of pituitary apoplexy during the second trimester. At the time of conception, most women were being treated with 5 mg bromocriptine. The majority of women had suspended medication in the 8th week of gestation. Caesarean rate was 48.6%. The maternal foetal outcome was favourable in all cases.

摘要

本文的目的是评估妊娠对患有泌乳素瘤的女性的影响、孕期维持/中断治疗可能产生的后果,并评估分娩方式及母婴产科结局。对2006年至2014年间我院所有患有泌乳素瘤的孕妇进行了一项回顾性研究。我们有35例患有泌乳素瘤的孕妇,其中2例在孕中期发生了垂体卒中。在受孕时,大多数女性正在接受5毫克溴隐亭治疗。大多数女性在妊娠第8周时停药。剖宫产率为48.6%。所有病例的母婴结局均良好。

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