Hospital Beatriz Ângelo, Loures, Portugal.
Rev Bras Ginecol Obstet. 2023 May;45(5):273-280. doi: 10.1055/s-0043-1770128. Epub 2023 Jun 20.
Pituitary apoplexy refers to a rare clinical syndrome consisting of signs and symptoms that occur due to rapid expansion of the contents of the . It can occur spontaneously or associated with pituitary tumors. It can have a broad clinical spectrum, but usually presents with severe headache, visual impairment and hypopituitarism. Sudden onset of symptoms associated to imagiologic confirmation makes the diagnosis. Surgical treatment is advised when there is important compression of the optic tract. We present a case report and a review of the literature on pituitary apoplexy in pregnancy. The cases were reviewed to obtain information on maternal characteristics, clinical presentation, diagnostic studies, therapeutic modalities and maternal and fetal outcomes. Our review found 36 cases of pituitary apoplexy in pregnancy. Most of the cases occurred in the second trimester of pregnancy and headache was the most frequent symptom at presentation. Surgical therapy was required in more than half of the patients. In what respect maternal and fetal outcomes, there were 3 cases of preterm delivery and one case of maternal death. Our clinical case and literature review reinforces the importance of an early diagnosis to avoid potential adverse consequences.
垂体卒中是一种罕见的临床综合征,其特征为由于 的内容物迅速扩张而引起的体征和症状。它可以自发发生,也可以与垂体瘤有关。它可以具有广泛的临床谱,但通常表现为严重头痛、视力障碍和垂体功能减退。症状的突然出现并结合影像学证实可做出诊断。当视神经束受到严重压迫时,建议进行手术治疗。我们报告了一例妊娠合并垂体卒中的病例,并对文献进行了复习。对病例进行了回顾,以获取有关孕产妇特征、临床表现、诊断研究、治疗方式以及母婴结局的信息。我们的复习发现了 36 例妊娠合并垂体卒中。大多数病例发生在妊娠中期,头痛是最常见的首发症状。超过一半的患者需要手术治疗。在母婴结局方面,有 3 例早产和 1 例产妇死亡。我们的临床病例和文献复习都强调了早期诊断的重要性,以避免潜在的不良后果。