Vitola E S, Bau C H D, Salum G A, Horta B L, Quevedo L, Barros F C, Pinheiro R T, Kieling C, Rohde L A, Grevet E H
Department of Psychiatry,ADHD Out-patient Program, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul,Porto Alegre,Brazil.
Post-Graduate Program in Epidemiology, Federal University of Pelotas,Pelotas,Brazil.
Psychol Med. 2017 Mar;47(4):744-754. doi: 10.1017/S0033291716002853. Epub 2016 Nov 21.
There are still uncertainties on the psychometric validity of the DSM-5 attention deficit hyperactivity disorder (ADHD) criteria for its use in the adult population. We aim to describe the adult ADHD phenotype, to test the psychometric properties of the DSM-5 ADHD criteria, and to calculate the resulting prevalence in a population-based sample in their thirties.
A cross-sectional evaluation using the DSM-5 ADHD criteria was carried out in 3574 individuals from the 1982 Pelotas Birth Cohort. Through receiver operator curve, latent and regression analyses, we obtained parameters on construct and discriminant validity. Still, prevalence rates were calculated for different sets of criteria.
The latent analysis suggested that the adult ADHD phenotype is constituted mainly by inattentive symptoms. Also, inattention symptoms were the symptoms most associated with impairment. The best cut-off for diagnosis was four symptoms, but sensitivity and specificity for this cut-off was low. ADHD prevalence rates were 2.1% for DSM-5 ADHD criteria and 5.8% for ADHD disregarding age-of-onset criterion.
The bi-dimensional ADHD structure proposed by the DSM demonstrated both construct and discriminant validity problems when used in the adult population, since inattention is a much more relevant feature in the adult phenotype. The use of the DSM-5 criteria results in a higher prevalence of ADHD when compared to those obtained by DSM-IV, and prevalence would increase almost threefold when considering current ADHD syndrome. These findings suggest a need for further refinement of the criteria for its use in the adult population.
《精神疾病诊断与统计手册》第五版(DSM - 5)中注意力缺陷多动障碍(ADHD)标准在成年人群体中的心理测量效度仍存在不确定性。我们旨在描述成人ADHD表型,测试DSM - 5 ADHD标准的心理测量特性,并计算在一个基于人群的三十多岁样本中的患病率。
对来自1982年佩洛塔斯出生队列的3574名个体进行了一项使用DSM - 5 ADHD标准的横断面评估。通过受试者工作特征曲线、潜在分析和回归分析,我们获得了关于结构效度和区分效度的参数。此外,还计算了不同标准集的患病率。
潜在分析表明,成人ADHD表型主要由注意力不集中症状构成。而且,注意力不集中症状是与功能损害最相关的症状。诊断的最佳临界值是四个症状,但该临界值的敏感性和特异性较低。DSM - 5 ADHD标准的ADHD患病率为2.1%,不考虑发病年龄标准的ADHD患病率为5.8%。
DSM提出的二维ADHD结构在应用于成年人群体时,显示出结构效度和区分效度方面的问题,因为注意力不集中在成人表型中是一个更为相关的特征。与DSM - IV获得的患病率相比,使用DSM - 5标准导致ADHD患病率更高,并且在考虑当前ADHD综合征时患病率几乎会增加两倍。这些发现表明需要进一步完善该标准以用于成年人群体。