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通过使用电路模拟理解门体分流的病理生理学

Understanding the Pathophysiology of Portosystemic Shunt by Simulation Using an Electric Circuit.

作者信息

Kim Moonhwan, Lee Keon-Young

机构信息

Department of Surgery, Inha University School of Medicine, Incheon 400-711, Republic of Korea.

出版信息

Biomed Res Int. 2016;2016:2097363. doi: 10.1155/2016/2097363. Epub 2016 Oct 27.

Abstract

Portosystemic shunt (PSS) without a definable cause is a rare condition, and most of the studies on this topic are small series or based on case reports. Moreover, no firm agreement has been reached on the definition and classification of various forms of PSS, which makes it difficult to compare and analyze the management. The blood flow can be seen very similar to an electric current, governed by Ohm's law. The simulation of PSS using an electric circuit, combined with the interpretation of reported management results, can provide intuitive insights into the underlying mechanism of PSS development. In this article, we have built a model of PSS using electric circuit symbols and explained clinical manifestations as well as the possible mechanisms underlying a PSS formation.

摘要

无明确病因的门体分流(PSS)是一种罕见病症,关于该主题的大多数研究都是小样本系列研究或基于病例报告。此外,对于各种形式的PSS的定义和分类尚未达成明确共识,这使得比较和分析治疗方法变得困难。血流情况与电流非常相似,受欧姆定律支配。使用电路模拟PSS,并结合对已报道治疗结果的解读,可以直观地洞察PSS发生的潜在机制。在本文中,我们使用电路符号构建了PSS模型,并解释了其临床表现以及PSS形成的可能机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78c/5102704/e8057cf1ab5e/BMRI2016-2097363.001.jpg

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