Neumann C, Baas H, Hefner R, Hör G
Abteilungen für Nuklearmedizin und Neurologie, Goethe-Universität, Frankfurt, BRD.
Nuklearmedizin. 1989 Jun;28(3):92-4.
The symptoms of Parkinson's disease often begin on one side of the body and continue to do so as the disease progresses. First SPECT results in 4 patients with hemiparkinsonism using 99mTc-HMPAO as perfusion marker are reported. Three patients exhibited reduced tracer uptake in the contralateral basal ganglia. One patient who was under therapy for 1 year, showed a different perfusion pattern with reduced uptake in both basal ganglia. These results might indicate reduced perfusion secondary to reduced striatal neuronal activity.
帕金森病的症状通常始于身体的一侧，并随着疾病进展持续如此。本文报道了4例以99mTc-HMPAO作为灌注标记物的偏侧帕金森病患者的首次单光子发射计算机断层扫描（SPECT）结果。3例患者对侧基底神经节示踪剂摄取减少。1例接受了1年治疗的患者表现出不同的灌注模式，双侧基底神经节摄取均减少。这些结果可能表明纹状体神经元活动减少继发灌注降低。
