从追踪至成年期的儿童纵向哮喘队列研究中得出的优势、缺陷与经验教训。
Strengths, Pitfalls, and Lessons from Longitudinal Childhood Asthma Cohorts of Children Followed Up into Adult Life.
作者信息
Tai Andrew
机构信息
Respiratory and Sleep Medicine, Women's and Children's Hospital, King William Road, North Adelaide, SA 5006, Australia; Robinson Research Institute, University of Adelaide, SA 5005, Australia.
出版信息
Biomed Res Int. 2016;2016:2694060. doi: 10.1155/2016/2694060. Epub 2016 Oct 31.
Asthma is a common problem worldwide and longitudinal studies of children followed up into adult life enable the assessment of clinical outcomes, examine the pattern of lung function outcomes, and importantly provide insight into aetiology and prognosis for patients with asthma. The aim of this review is to examine the major childhood asthma cohort studies which have continued into adult life, describing the strengths and weaknesses and the lessons that can be learnt regarding pathophysiology and potential future directions for research.
哮喘是全球范围内的常见问题，对儿童进行追踪随访直至成年的纵向研究能够评估临床结局、检查肺功能结局模式，并且重要的是能深入了解哮喘患者的病因和预后。本综述的目的是审视那些持续追踪至成年期的主要儿童哮喘队列研究，描述其优缺点以及在病理生理学方面可以吸取的经验教训和未来潜在的研究方向。
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