Yalo Bertrand, Pop Raoul, Zinchenko Ielyzaveta, Diaconu Mihaela, Chibbaro Salvatore, Manisor Monica, Wolff Valerie, Beaujeux Remy
Department of Vascular Neurology, Hopitaux universitaires de Strasbourg, Strasbourg, Alsace, France.
Department of Interventional Radiology, Institut Hospitalo-Universitaire, Strasbourg, France.
BMJ Case Rep. 2016 Nov 9;2016:bcr2016012680. doi: 10.1136/bcr-2016-012680.
We report a case of interhemispheric and bifrontal cortical superficial siderosis in association with two intracranial aneurysms. The patient had no clinical history suggestive of aneurysm rupture, no feature of amyloid angiopathy or other apparent etiology for cortical siderosis. We performed high resolution brain MRI with dark blood T1 sequences before and after IV contrast injection. An anterior communicating aneurysm showed partial wall enhancement on the posterior wall whereas a left posterior communicating aneurysm did not. In the light of recent reports of the association of wall enhancement with unstable aneurysms, we considered wall enhancement to be a marker of inflammation and remodeling of the aneurysm wall, resulting in chronic hemorrhagic suffusion in the subarachnoid spaces. To our knowledge, this is the first report offering proof for a possible link between apparently unruptured aneurysms and cortical siderosis.
我们报告一例伴有两个颅内动脉瘤的大脑半球间及双额叶皮质表面铁沉积症。该患者无提示动脉瘤破裂的临床病史,无淀粉样血管病特征或其他明显的皮质铁沉积病因。我们在静脉注射造影剂前后采用黑血T1序列进行了高分辨率脑部MRI检查。前交通动脉瘤后壁出现部分壁强化,而左侧后交通动脉瘤未出现。鉴于最近有关壁强化与不稳定动脉瘤相关的报道,我们认为壁强化是动脉瘤壁炎症和重塑的标志,导致蛛网膜下腔慢性出血性渗出。据我们所知,这是首份为明显未破裂的动脉瘤与皮质铁沉积症之间可能存在的联系提供证据的报告。