Clinical Evaluation Research Unit, Kingston General Hospital, Kingston, Ontario, Canada.
Department of Public Health Sciences, Queen's University, Kingston, Ontario, Canada.
JPEN J Parenter Enteral Nutr. 2018 Feb;42(2):308-317. doi: 10.1177/0148607116673301. Epub 2017 Dec 12.
The purpose of this study was to determine what was "best achievable practice" with the implementation of a novel enteral feeding protocol (Enhanced Protein-Energy Provision via the Enteral Route Feeding Protocol [PEP uP protocol]).
This study was a multicenter quality improvement collaborative wherein we describe nutrition practices and outcomes within PEP uP sites. We report the minimum, average, and maximal site-level performance on aspects related to nutrition practices and outcomes.
In 2014, 7 intensive care units (ICUs) in the United States implemented the PEP uP protocol. On average, over the first 5 ICU days, patients received 35% (site range, 26%-53%) of their prescribed energy requirements and 42% (site range, 29%-66%) of their prescribed protein requirements from enteral nutrition. In PEP uP sites, 71% (site range, 58%-95%) of patients received a semidigested formula within 72 hours of admission to the ICU, 72% had a volume-based goal as the initial feeding strategy (site range, 47%-100%), 56% had prophylactic protein supplements (site range, 0%-100%), and 19% received prophylactic motility agents (site range, 0%-85%).
There was variable success with the implementation of the different components of the PEP uP protocol. Improving the implementation of the various components may further increase nutrition delivery.
本研究旨在确定新型肠内喂养方案(通过肠内途径给予强化蛋白质-能量供给方案 [PEP uP 方案])实施的“最佳可行实践”是什么。
这是一项多中心质量改进合作研究,我们在此描述 PEP uP 实施地点的营养实践和结果。我们报告与营养实践和结果相关的方面的最低、平均和最高站点水平表现。
2014 年,美国的 7 个重症监护病房(ICUs)实施了 PEP uP 方案。平均而言,在前 5 天 ICU 住院期间,患者接受的肠内营养提供的能量需求分别为 35%(站点范围为 26%-53%)和蛋白质需求的 42%(站点范围为 29%-66%)。在 PEP uP 实施地点,71%(站点范围为 58%-95%)的患者在入住 ICU 后 72 小时内接受了半消化配方,72%(站点范围为 47%-100%)的患者以容量为基础作为初始喂养策略,56%(站点范围为 0%-100%)的患者使用预防性蛋白质补充剂,19%(站点范围为 0%-85%)的患者使用预防性促动力剂。
PEP uP 方案不同组成部分的实施存在不同程度的成功。改善各种组成部分的实施情况可能会进一步增加营养输送。