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双侧单孔胸腔镜扩大胸腺切除术治疗胸腺瘤合并重症肌无力:病例报告

Bilateral single-port thoracoscopic extended thymectomy for management of thymoma and myasthenia gravis: case report.

作者信息

Caronia Francesco Paolo, Fiorelli Alfonso, Arrigo Ettore, Trovato Sebastiano, Santini Mario, Monte Attilio Ignazio Lo

机构信息

Thoracic Surgery Unit, Istituto Oncologico del Mediterraneo, Catania, Italy.

Thoracic Surgery Unit, Second University of Naples, Piazza Miraglia, 2, I-80138, Naples, Italy.

出版信息

J Cardiothorac Surg. 2016 Nov 22;11(1):153. doi: 10.1186/s13019-016-0547-3.

Abstract

BACKGROUND

Video-assisted thoracoscopy is become a widely accepted approach for the resection of anterior mediastinal masses, including thymoma. The current trend is to reduce the number of ports and minimize the length of incisions to further decrease postoperative pain, chest wall paresthesia, and length of hospitalization. Herein, we reported an extended resection of thymoma in a patient with myasthenia gravis through an uniportal bilateral thoracoscopic approach.

CASE PRESENTATION

A 74 years old woman with myasthenia gravis was referred to our attention for management of a 3.5 cm, well capsulate, thymoma. All laboratory and cardio-pulmonary tests were within normal; thus, she was scheduled for thymoma resection through an uniportal bilateral thoracoscopic approach. Under general anaesthesia and selective intubation, the patient was placed in a 60° right lateral decubitus. A 3 cm skin incision was performed in the fourth right intercostal space and, through that a 30° video-camera and working instruments were inserted without rib spreading. After complete dissection of the thymus and mediastinal fat, the contralateral pleura was opened, and, through that the specimen was pushed into the left pleural cavity. Then, the patient was placed in the left lateral decubitus. Similarly to the right side procedure, a 3-cm incision was performed in the fourth left intercostal space to complete thymic dissection and retrieve the specimen. No intraoperative and post-operative complications were found. The patient was discharged four days later. Pathological examination revealed a type A thymoma (Masaoka stage I). No recurrence was found at 18 months of follow-up CONCLUSIONS: Bilateral single-port thoracoscopy is an available procedure for management of thymoma associated with myasthenia gravis. The less post-operative pain, the reduction of hospital stay and the better esthetic results are all potential advantages of this approach over traditional technique. Obviously, our impression should be validated by larger studies in terms of long-term oncological outcomes.

摘要

背景

电视辅助胸腔镜已成为切除包括胸腺瘤在内的前纵隔肿物广泛接受的方法。当前的趋势是减少切口数量并使切口长度最小化,以进一步减轻术后疼痛、胸壁感觉异常和缩短住院时间。在此,我们报告了通过单孔双侧胸腔镜方法对一名重症肌无力患者进行胸腺瘤扩大切除术。

病例介绍

一名74岁重症肌无力女性因3.5 cm、包膜完整的胸腺瘤前来就诊。所有实验室及心肺检查均正常;因此,她被安排通过单孔双侧胸腔镜方法进行胸腺瘤切除术。在全身麻醉和选择性插管下,患者取60°右侧卧位。在右第四肋间做一个3 cm的皮肤切口,通过该切口在不撑开肋骨的情况下插入一个30°摄像头和操作器械。在完全游离胸腺和纵隔脂肪后,打开对侧胸膜,通过该胸膜将标本推入左胸腔。然后,患者转为左侧卧位。与右侧手术类似,在左第四肋间做一个3 cm切口以完成胸腺游离并取出标本。未发现术中及术后并发症。患者于四天后出院。病理检查显示为A型胸腺瘤(Masaoka I期)。随访18个月未发现复发。

结论

双侧单孔胸腔镜是治疗重症肌无力相关胸腺瘤的一种可行方法。与传统技术相比,该方法术后疼痛较轻、住院时间缩短且美观效果更好,这些都是其潜在优势。显然,我们的观点应通过关于长期肿瘤学结局的更大规模研究来验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ca/5120463/0fcb7f45b162/13019_2016_547_Fig1_HTML.jpg

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