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伊朗西南部糖尿病孕妇弓形虫病血清阳性率

Seroprevalence of toxoplasmosis in diabetic pregnant women in southwestern of Iran.

作者信息

Saki Jasem, Shafieenia Shahla, Foroutan-Rad Masoud

机构信息

Department of Medical Parasitology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, P. O. Box: 613715794, Ahvaz, Islamic Republic of Iran ; Health Institute, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran.

Department of Medical Parasitology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, P. O. Box: 613715794, Ahvaz, Islamic Republic of Iran.

出版信息

J Parasit Dis. 2016 Dec;40(4):1586-1589. doi: 10.1007/s12639-015-0735-4. Epub 2016 Jan 23.

Abstract

To investigate anti- IgG and IgM antibodies in diabetic pregnant women in Ahvaz, southwest of Iran this experiment was performed. In current study the sera of 110 diabetic pregnant women as well as 110 non diabetic pregnant women referred to the hospitals affiliated with the Ahvaz Jundishapur University of Medical Sciences were assessed for anti- IgG and IgM antibodies by ELISA and IFA methods. The ELISA assessments showed that 47 (42.7 %) and 3 (2.7 %) of diabetic women were positive for IgG and IgM antibodies, respectively. However, in the control group, 24 individuals (21.81 %) were positive for IgG antibody but no detection for IgM antibody. According to IFA method, 46 (41.8 %) and 3 (2.7 %) of diabetic women were positive for IgG and IgM antibodies, respectively, while in control group, 21 individuals (19.09 %) were positive for IgG antibody. In this method, IgM antibody was negative for all samples of control group (0 %). In both methods, the values obtained in the case group were significantly higher than those in the control group ( < 0.05). Prevalence of anti- IgG and IgM antibodies in diabetic pregnant women was higher than that in non-diabetic pregnant women. It seems that screening tests for seeking patients and teaching the transmission routes should be considered as prenatal cares for diabetic women.

摘要

为了调查伊朗西南部阿瓦士地区糖尿病孕妇体内的抗IgG和IgM抗体,进行了本实验。在当前研究中,采用酶联免疫吸附测定法(ELISA)和间接荧光抗体法(IFA)对转诊至阿瓦士贾undishapur医科大学附属医院的110名糖尿病孕妇以及110名非糖尿病孕妇的血清进行了抗IgG和IgM抗体评估。ELISA评估显示,糖尿病女性中分别有47名(42.7%)和3名(2.7%)的IgG和IgM抗体呈阳性。然而,在对照组中,有24人(21.81%)的IgG抗体呈阳性,但未检测到IgM抗体。根据IFA方法,糖尿病女性中分别有46名(41.8%)和3名(2.7%)的IgG和IgM抗体呈阳性,而在对照组中,有21人(19.09%)的IgG抗体呈阳性。在该方法中,对照组所有样本的IgM抗体均为阴性(0%)。在两种方法中,病例组获得的值均显著高于对照组(<0.05)。糖尿病孕妇中抗IgG和IgM抗体的患病率高于非糖尿病孕妇。似乎应将寻找患者的筛查试验和传授传播途径作为糖尿病女性产前护理的内容。

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