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[主动脉肠瘘——上消化道出血的一种罕见但重要的病因]

[The aorto-enteric fistula--a rare, but important cause of upper gastrointestinal hemorrhage].

作者信息

Lenzen R, Hengels K J, Kniemeyer H W, Berges W

机构信息

Medizinische Klinik und Poliklinik der Universität Düsseldorf, Abteilung für Gastroenterologie.

出版信息

Z Gastroenterol. 1989 May;27(5):267-71.

PMID:2787946
Abstract

During the last two years two patients with upper gastrointestinal bleeding caused by an aortoenteric fistula were admitted to the hospital. The first patient had a primary fistula between an arteriosclerotic aneurysm of the abdominal aorta and the duodenum. The second patient had an infected aortobifemoral graft which had penetrated into the upper jejunum. The aortoenteric fistula is one of the very rare causes of upper gastrointestinal bleeding. Referring to previous surgery at the aorta a primary and secondary type of fistula are differentiated. The primary fistula often induces a small initial bleeding followed by a severe hemorrhage with hematemesis and melaena. The secondary form is mostly caused by bacterial infection of the graft. Recurrent fever attacks are a common clinical symptom without any evidence of the origin of the bacteriemia. Principally the combination of upper gastrointestinal bleeding and aortic graft is always suspicious of an aortoenteric fistula. The most important preoperative examinations are endoscopy, computed tomography scan, and arteriography. The treatment must be surgical. Either a synthetic graft surrounded by omentum is implanted or an axillobifemoral or aortobifemoral bypass is constructed. Even if the diagnosis is made early mortality of the disease is about 20-30%.

摘要

在过去两年中,有两名因主动脉肠瘘导致上消化道出血的患者入院。首例患者是腹主动脉粥样硬化性动脉瘤与十二指肠之间存在原发性瘘。第二例患者是感染的主动脉双股人工血管穿破至上段空肠。主动脉肠瘘是上消化道出血极为罕见的病因之一。根据主动脉既往手术史,可区分原发性和继发性瘘。原发性瘘常先有少量初始出血,随后出现严重出血,伴有呕血和黑便。继发性瘘主要由人工血管的细菌感染引起。反复发热发作是常见的临床症状,且无任何菌血症来源的证据。原则上,上消化道出血与主动脉人工血管并存总是怀疑有主动脉肠瘘。最重要的术前检查是内镜检查、计算机断层扫描和动脉造影。治疗必须采取手术方式。要么植入带网膜包裹的人工血管,要么构建腋双股或主动脉双股旁路。即使早期做出诊断,该病的死亡率仍约为20% - 30%。

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