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在对一名未被怀疑患有冷凝集素病的患者进行全身降温之前,在心脏停搏液血库中检测到冷凝集现象。

Detection of cold hemagglutination in a blood cardioplegia unit before systemic cooling of a patient with unsuspected cold agglutinin disease.

作者信息

Dake S B, Johnston M F, Brueggeman P, Barner H B

机构信息

Department of Surgery, St. Louis University School of Medicine, Missouri 63104.

出版信息

Ann Thorac Surg. 1989 Jun;47(6):914-5. doi: 10.1016/0003-4975(89)90035-0.

DOI:10.1016/0003-4975(89)90035-0
PMID:2787974
Abstract

A case is described in which hemagglutination occurred intraoperatively in cold blood flushed through the blood cardioplegia delivery system from a patient with unsuspected cold agglutinin disease. On initiating cardiopulmonary bypass and then selectively cooling the perfusate in the blood cardioplegia delivery system before inducing systemic cooling, it is possible to check for cold agglutination. Routine use of this technique may be worthwhile to detect cold agglutination in vitro before systemic cooling is begun in the rare patient with unsuspected cold agglutinins.

摘要

本文描述了一例病例,在使用冷血心脏停搏液输送系统冲洗来自一名未被怀疑患有冷凝集素病患者的血液时,术中发生了血凝反应。在开始体外循环,然后在诱导全身降温前选择性地冷却心脏停搏液输送系统中的灌注液时,可以检查是否存在冷凝集反应。对于罕见的未被怀疑患有冷凝集素的患者,在开始全身降温前常规使用该技术可能有助于在体外检测冷凝集反应。

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引用本文的文献

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Cold Agglutinin Autoantibodies in a Patient without a Visible Coronary Sinus Ostium: Strategies for Myocardial Protection without Using Retrograde Cardioplegia.无可见冠状窦口患者的冷凝集素自身抗体:不使用逆行心脏停搏进行心肌保护的策略
J Extra Corpor Technol. 2016 Jun;48(2):79-82.
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Agglutinins and cardiac surgery: a web based survey of cardiac anaesthetic practice; questions raised and possible solutions.
凝集素与心脏手术:一项基于网络的心脏麻醉实践调查;提出的问题及可能的解决方案。
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