Vărcuş Flore, Beuran Mircea, Lica Ioan, Turculet Claudiu, Cotarlet Adrian Valentin, Georgescu Stefan, Vintila Dan, Sabău Dan, Sabau Alexandru, Ciuce Constantin, Bintintan Vasile, Georgescu Eugen, Popescu Razvan, Tarta Cristi, Surlin Valeriu
Surgical Clinic 2, Clinical Emergency County Hospital, Victor Babes University of Medicine and Pharmacy, Str. I. Bulbuca, No. 10, Timisoara, Romania.
Surgical Clinic 2, Clinical Emergency Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
World J Surg. 2017 Apr;41(4):948-953. doi: 10.1007/s00268-016-3821-6.
The incidence of patients presenting with perforated peptic ulcers (PPU) has decreased during the last decades. At the same time, a laparoscopic approach to this condition has been adopted by increased number of surgeons. The aim of this study was to evaluate the early postoperative results of the laparoscopic treatment of perforated peptic ulcer performed in eight Romanian surgical centers with extensive experience in laparoscopic surgery.
Between 2009 and 2013, 297 patients with perforated peptic ulcer were operated in the eight centers participating in this retrospective study. The patients' charts were reviewed for demographics, surgical procedure, complications and short-term outcomes.
Boey score of 0 was found in 122 patients (41.1%), Boey 1 in 169 (56.9%), Boey 3 in 6 (2.0%). For 145 (48.8%) patients, primary suture repair was performed, in 146 (49.2%) primary suture repair with omentopexy. There were 6 (2.0%) conversions to open surgery. The operative time was between 25 and 120 min, with a mean of 68 min. Two (0.7%) deaths were noted. Mean hospital stay was 5.5 days, ranges 3-25 days. Postoperative complications included: 7 (2.4%) superficial surgical site infections, 5 (1.6%) cardiovascular, 3 (1.0%) pulmonary, 2 (0.7%) duodenal leakages, 3 (1.0%) deep space infections and 1 (0.3%) upper digestive hemorrhage.
This study shows that the laparoscopic approach for PPU is feasible; the procedure is safe, with no increased risk of duodenal fistulae or residual intraperitoneal abscesses. We now consider the laparoscopic approach for PPU as the "gold standard" in patients with Boey score 0 or 1.
在过去几十年中,患有消化性溃疡穿孔(PPU)的患者发病率有所下降。与此同时,越来越多的外科医生采用腹腔镜方法治疗这种疾病。本研究的目的是评估在罗马尼亚八个具有丰富腹腔镜手术经验的外科中心进行的腹腔镜治疗消化性溃疡穿孔的早期术后结果。
2009年至2013年期间,参与这项回顾性研究的八个中心对297例消化性溃疡穿孔患者进行了手术。对患者的病历进行了人口统计学、手术程序、并发症和短期结果的审查。
122例患者(41.1%)的Boey评分为0,169例(56.9%)为Boey 1,6例(2.0%)为Boey 3。145例(48.8%)患者进行了一期缝合修补,146例(49.2%)进行了带网膜固定的一期缝合修补。有6例(2.0%)转为开放手术。手术时间在25至120分钟之间,平均为68分钟。记录到2例(0.7%)死亡。平均住院时间为5.5天,范围为3至25天。术后并发症包括:7例(2.4%)浅表手术部位感染、5例(1.6%)心血管并发症、3例(1.0%)肺部并发症、2例(0.7%)十二指肠渗漏、3例(1.0%)深部间隙感染和1例(0.3%)上消化道出血。
本研究表明,腹腔镜治疗PPU是可行的;该手术是安全的,十二指肠瘘或腹腔内残余脓肿的风险没有增加。我们现在认为,对于Boey评分为0或1的患者,腹腔镜治疗PPU可作为“金标准”。