Suh Ga-Young, Fleischmann Dominik, Beygui Ramin E, Cheng Christopher P
Department of Surgery, Stanford University, 300 Pasteur Dr. Suite H3600, Stanford, CA, 94305-5642, USA.
Department of Radiology, Stanford University, Stanford, CA, USA.
Int J Comput Assist Radiol Surg. 2017 May;12(5):811-819. doi: 10.1007/s11548-016-1499-8. Epub 2016 Nov 23.
To quantify cardiac and respiratory deformations of the thoracic aorta after ascending aortic graft repair.
Eight patients were scanned with cardiac-resolved computed tomography angiography during inspiratory/expiratory breath-holds. Aortic centerlines and lumen were extracted to compute the arclength, curvature, angulation, and cross-section shape.
From systole to diastole, the angle of graft [Formula: see text] arch increased by 2.4[Formula: see text] ± 1.8[Formula: see text] (P < 0.01) and the angle of arch [Formula: see text] descending aorta decreased by 2.4[Formula: see text] ± 2.6[Formula: see text] (P < 0.05), while the effective diameter of the proximal arch decreased by 2.4 ± 1.9% (P < 0.01), a greater change than those of the graft or distal arch (P < 0.05). From inspiration to expiration, the angle of graft [Formula: see text] arch increased by 2.8[Formula: see text] ± 2.6[Formula: see text] (P < 0.02) with the peak curvature increase (P < 0.05). Shorter graft length was correlated with greater cardiac-induced graft [Formula: see text] arch angulation, and longer graft length was correlated with greater respiratory-induced arch [Formula: see text] descending aorta angulation (R [Formula: see text] 0.50).
The thoracic aorta changed curvature and angulation with cardiac and respiratory influences, driven by aortic root and arch motion. The thoracic aortic geometry and deformation are correlated with the ascending aortic graft length.
量化升主动脉移植修复术后胸主动脉的心脏和呼吸变形。
8例患者在吸气/呼气屏气期间接受心脏分辨计算机断层扫描血管造影。提取主动脉中心线和管腔以计算弧长、曲率、角度和横截面形状。
从收缩期到舒张期,移植物[公式:见正文]弓的角度增加2.4[公式:见正文]±1.8[公式:见正文](P<0.01),弓[公式:见正文]降主动脉的角度减少2.4[公式:见正文]±2.6[公式:见正文](P<0.05),而近端弓的有效直径减少2.4±1.9%(P<0.01),变化大于移植物或远端弓(P<0.05)。从吸气到呼气,移植物[公式:见正文]弓的角度增加2.8[公式:见正文]±2.6[公式:见正文](P<0.02),曲率增加峰值(P<0.05)。较短的移植物长度与更大的心脏诱导的移植物[公式:见正文]弓角度相关,较长的移植物长度与更大的呼吸诱导的弓[公式:见正文]降主动脉角度相关(R[公式:见正文]0.50)。
胸主动脉在心脏和呼吸影响下改变曲率和角度,由主动脉根部和弓的运动驱动。胸主动脉的几何形状和变形与升主动脉移植物长度相关。