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埃塞俄比亚东部吉吉加镇居民中与化妆品使用相关的不良事件及决定因素

Cosmetics Use-Related Adverse Events and Determinants Among Jigjiga Town Residents, Eastern Ethiopia.

作者信息

Bilal Arebu I, Tilahun Zelalem, Osman Ebrahim D, Mulugeta Anwar, Shekabdulahi Muktar, Berhe Derbew Fikadu

机构信息

Department of Pharmaceutics and Social Pharmacy, College of Health Sciences, School of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia.

Department of Pharmacy, Jigjiga Health Sciences College, Jigjiga, Ethiopia.

出版信息

Dermatol Ther (Heidelb). 2017 Mar;7(1):143-153. doi: 10.1007/s13555-016-0157-y. Epub 2016 Nov 23.

Abstract

INTRODUCTION

Non-medicated cosmetics use is very common among the Ethiopian population. However, little is known about these products' related adverse events. The aim of this study was to assess the prevalence and determinants of cosmetics-related adverse events among Jigjiga Town residents, Eastern Ethiopia.

METHODS

A community-based cross-sectional study design was conducted in May and June 2014. Semi-structured interviews were used to collect cosmetics use pattern and related adverse events. For assessing determinants, logistic regression was used and statistical significance was set at p < 0.05.

RESULTS

Overall, 600 participants were approached with a 93% response rate. Ninety-three percent (n = 521) of them reported the use of cosmetics at least once within 2 weeks prior to this study, and of these, 229 (44%) used traditional herbal cosmetics along with modern cosmetics. A total of 342 (61%) reported experiencing adverse events of which the most common reported were: allergic reactions, 149 (36%); the appearance of acne, 66 (16%); and hirsutism, 52 (12.5%). The occurrence of cosmetics-related adverse events were significantly associated with the number of cosmetics used per day, the frequency of use, mixing of different types of cosmetics together, and mixing of cosmetics with water or saliva.

CONCLUSION

A higher proportion of cosmetic users reported experiencing at least one adverse event. The number of cosmetic products and frequency of use were important predictors for experiencing adverse events. This implies the need to consider safety concerns related to cosmetic use. Approaches to address such issues may include awareness creation programs and promoting the concept of cosmetovigilance among cosmetic sellers, users, and other stakeholders.

摘要

引言

在埃塞俄比亚人群中,非药用化妆品的使用非常普遍。然而,对于这些产品相关的不良事件却知之甚少。本研究的目的是评估埃塞俄比亚东部吉吉加镇居民中与化妆品相关不良事件的患病率及其决定因素。

方法

2014年5月和6月进行了一项基于社区的横断面研究设计。采用半结构化访谈收集化妆品使用模式及相关不良事件。为评估决定因素,使用了逻辑回归,设定统计学显著性为p < 0.05。

结果

总体而言,共接触了600名参与者,应答率为93%。其中93%(n = 521)报告在本研究前2周内至少使用过一次化妆品,其中229人(44%)同时使用传统草药化妆品和现代化妆品。共有342人(61%)报告经历过不良事件,其中最常见的是:过敏反应,149人(36%);痤疮出现,66人(16%);多毛症,52人(1

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b914/5336426/407243eecbbf/13555_2016_157_Fig1_HTML.jpg

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