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关于学校牙科筛查与不进行筛查对改善儿童口腔健康效果的随机对照试验的系统评价和荟萃分析。

Systematic review and meta-analysis of randomised controlled trials on the effectiveness of school-based dental screening versus no screening on improving oral health in children.

作者信息

Joury Easter, Bernabe Eduardo, Sabbah Wael, Nakhleh Kamal, Gurusamy Kurinchi

机构信息

Population and Patient Health, King's College London Dental Institute, Denmark Hill Campus, Bessemer Road, London, SE5 9RS, United Kingdom.

Angle House Orthodontics, London, N18 1JX, United Kingdom.

出版信息

J Dent. 2017 Mar;58:1-10. doi: 10.1016/j.jdent.2016.11.008. Epub 2016 Nov 22.

Abstract

OBJECTIVES

The current study aimed to evaluate the effectiveness of school-based dental screening versus no screening on improving oral health in children aged 3-18 years by a systematic review and meta-analysis of randomised controlled trials.

SOURCES AND STUDY SELECTION

Three sets of independent reviewers searched MEDLINE, EMBASE, Web of Science and other sources through April 2016 to identify published and nonpublished studies without language restrictions and extracted data.

DATA

Primary outcomes included prevalence and mean number of teeth with caries, incidence of dental attendance and harms of screening. Cochrane's criteria for risk of bias assessment were used.

RESULTS

A total of five cluster RCTs (of unclear or high risk of bias), including 28,442 children, were meta-analysed. For an intracluster correlation coefficient of 0.030, there was no statistically significant difference in dental attendance between children who received dental screening and those who did not receive dental screening (RR 1.11, 95% 0.97, 1.27). The Chi-square test for heterogeneity and the Higgin's I value indicated a substantial heterogeneity. Only one study reported the prevalence and mean number of deciduous and permanent teeth with dental caries and found no significant differences between the screening and no screening groups.

CONCLUSIONS

There is currently no evidence to support or refute the clinical benefits or harms of dental screening. Routine dental screening may not increase the dental attendance of school children, but there is a lot of uncertainty in this finding because of the quality of evidence.

CLINICAL SIGNIFICANCE

Evidence from the reviewed trials suggests no clinical benefit from school-based screening in improving children's oral health. However, there is a lot of uncertainty in this finding because of the quality of evidence. There is a need to conduct a well-designed trial with an intensive follow-up arm and cost-effectiveness analysis.

SYSTEMATIC REVIEW REGISTRATION NUMBER

CRD42016038828 (PROSPERO database).

摘要

目的

本研究旨在通过对随机对照试验的系统评价和荟萃分析,评估以学校为基础的牙科筛查与不进行筛查相比,对改善3至18岁儿童口腔健康的有效性。

资料来源与研究选择

三组独立的评审人员检索了截至2016年4月的MEDLINE、EMBASE、科学引文索引及其他来源,以识别已发表和未发表的研究,无语言限制,并提取数据。

数据

主要结局包括龋齿患病率和平均患龋牙数、看牙就诊率及筛查的危害。采用Cochrane偏倚风险评估标准。

结果

共对5项整群随机对照试验(偏倚风险不明确或高)进行了荟萃分析,涉及28442名儿童。对于组内相关系数为0.030的情况,接受牙科筛查的儿童与未接受牙科筛查的儿童在看牙就诊率方面无统计学显著差异(风险比1.11,95%置信区间0.97,1.27)。异质性的卡方检验和希金斯I值表明存在实质性异质性。仅有一项研究报告了乳牙和恒牙患龋的患病率及平均患龋牙数,发现筛查组与非筛查组之间无显著差异。

结论

目前尚无证据支持或反驳牙科筛查的临床益处或危害。常规牙科筛查可能不会增加学童的看牙就诊率,但由于证据质量,这一发现存在很多不确定性。

临床意义

所审查试验的证据表明,以学校为基础的筛查对改善儿童口腔健康无临床益处。然而,由于证据质量,这一发现存在很多不确定性。需要进行一项设计良好的试验,设置强化随访组并进行成本效益分析。

系统评价注册号

CRD42016038828(PROSPERO数据库)

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