Sanju Himanshu Kumar, Bohra Vaishnavi, Sinha Sujeet Kumar
Department of Audiology and Speech Language Pathology, Amity Medical School, Amity University, Gurgaon, 122413, Haryana, India.
Department of Audiology, All India Institute of Speech and Hearing, Mysore, 570006, Karnataka, India.
Eur Arch Otorhinolaryngol. 2017 Apr;274(4):2041-2048. doi: 10.1007/s00405-016-4402-x. Epub 2016 Nov 24.
This study aimed at characterizing the gap detection threshold (GDT) and speech evoked ABR (SABR) in younger and middle-aged individuals. Two groups of subjects were participated in the study which includes 15 young adults in the age range of 15-25 years and 15 middle-aged individuals in the age range of 40-60 years. SABR with stimulus/da/of 40 ms and GDT were investigated on both groups. For SABR, Mann-Whitney U test revealed that ageing has significantly adverse effect on the encoding of F1 and F2 at brainstem level. However, no significant effect of ageing (till middle age) on the encoding of F0 was observed in present study. Mann-Whitney U test also showed significant longer latency of wave V in middle-aged individuals compared to younger adults. Furthermore, GDT was significantly better in younger adults compared to middle-aged individuals according to Mann-Whitney U test. This study also revealed no significant correlation between GDT and F0, F1, F2 for younger as well as middle-aged individuals. The findings of this study showed poor encoding of certain aspects of speech at brainstem level in middle-aged individuals compared to younger adults. This study also revealed deterioration of auditory processes in middle-aged individuals.
本研究旨在表征年轻和中年个体的间隙检测阈值（GDT）和言语诱发听觉脑干反应（SABR）。两组受试者参与了该研究，其中包括15名年龄在15至25岁之间的年轻成年人和15名年龄在40至60岁之间的中年个体。对两组受试者均进行了刺激/da/时长为40毫秒的SABR和GDT研究。对于SABR，曼-惠特尼U检验显示，衰老对脑干水平F1和F2的编码有显著不利影响。然而，在本研究中未观察到衰老（直至中年）对F0编码有显著影响。曼-惠特尼U检验还显示，与年轻成年人相比，中年个体的V波潜伏期显著更长。此外，根据曼-惠特尼U检验，年轻成年人的GDT明显优于中年个体。本研究还表明，年轻和中年个体的GDT与F0、F1、F2之间均无显著相关性。本研究结果显示，与年轻成年人相比，中年个体在脑干水平对言语某些方面的编码较差。本研究还揭示了中年个体听觉过程的退化。
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