基于聚（2,6-二羟基萘）膜修饰的丝网印刷碳电极的过氧亚硝酸盐传感器。

Peroxynitrite Sensor Based on a Screen Printed Carbon Electrode Modified with a Poly(2,6-dihydroxynaphthalene) Film.

作者信息

Hosu Ioana Silvia, Constantinescu-Aruxandei Diana, Jecu Maria-Luiza, Oancea Florin, Badea Doni Mihaela

机构信息

National Institute for Research & Development in Chemistry and Petrochemistry-ICECHIM, Biotechnology Department, 202 Spl. Independentei, Sector 6, Bucharest, Romania.

出版信息

Sensors (Basel). 2016 Nov 23;16(11):1975. doi: 10.3390/s16111975.

DOI:10.3390/s16111975

PMID:27886072

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5134633/

Abstract

For the first time the electropolymerization of 2,6-dihydroxynaphthalene (2,6-DHN) on a screen printed carbon electrode (SPCE) was investigated and evaluated for peroxynitrite (PON) detection. Cyclic voltammetry was used to electrodeposit the poly(2,6-DHN) on the carbon electrode surface. The surface morphology and structure of poly(2,6-DHN) film were investigated by SEM and FTIR analysis, and the electrochemical features by cyclic voltammetry. The poly(2,6-DHN)/SPCE sensor showed excellent electrocatalytic activity for PON oxidation in alkaline solutions at very low potentials (0-100 mV vs. Ag/AgCl pseudoreference). An amperometric FIA (flow injection analysis) system based on the developed sensor was optimized for PON measurements and a linear concentration range from 2 to 300 μM PON, with a LOD of 0.2 μM, was achieved. The optimized sensor inserted in the FIA system exhibited good sensitivity (4.12 nA·μM), selectivity, stability and intra-/inter-electrode reproducibility for PON determination.

摘要

首次研究并评估了在丝网印刷碳电极（SPCE）上进行2,6 - 二羟基萘（2,6 - DHN）的电聚合用于过氧亚硝酸盐（PON）检测。采用循环伏安法在碳电极表面电沉积聚（2,6 - DHN）。通过扫描电子显微镜（SEM）和傅里叶变换红外光谱（FTIR）分析研究了聚（2,6 - DHN）膜的表面形态和结构，并通过循环伏安法研究了其电化学特性。聚（2,6 - DHN）/SPCE传感器在碱性溶液中对PON氧化在非常低的电位（相对于Ag/AgCl伪参比电极0 - 100 mV）下表现出优异的电催化活性。基于所开发传感器的安培流动注射分析（FIA）系统针对PON测量进行了优化，实现了2至300 μM PON的线性浓度范围，检测限为0.2 μM。插入FIA系统中的优化传感器在PON测定中表现出良好的灵敏度（4.12 nA·μM）、选择性、稳定性以及电极内/电极间的重现性。