心脏再同步治疗期间的心房颤动

Atrial Fibrillation During Cardiac Resynchronization Therapy.

作者信息

Kloosterman Mariëlle, Maass Alexander H, Rienstra Michiel, Van Gelder Isabelle C

机构信息

Department of Cardiology, Thoraxcenter, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.

出版信息

Heart Fail Clin. 2017 Jan;13(1):179-192. doi: 10.1016/j.hfc.2016.07.014.

DOI:10.1016/j.hfc.2016.07.014

PMID:27886922

Abstract

The landmark trials on cardiac resynchronization therapy (CRT) have focused on patients with sinus rhythm at inclusion. Little data are available on the efficacy of CRT in patients with atrial fibrillation (AF), while AF has a high prevalence (20-40%) among patients receiving CRT. This review focuses on the detrimental effect of AF on CRT response and discusses management of patients with AF during CRT. Uncertainty remains as to which thresholds of AF burden can lead to a reduced response to CRT and every effort should be made in trying to assess and guarantee successful biventricular pacing in patients with AF.

摘要

心脏再同步治疗（CRT）的里程碑式试验主要关注纳入时为窦性心律的患者。关于CRT在心房颤动（AF）患者中的疗效，目前可用数据较少，而AF在接受CRT的患者中患病率较高（20%-40%）。本综述重点关注AF对CRT反应的不利影响，并讨论CRT期间AF患者的管理。AF负荷达到何种阈值会导致CRT反应降低仍不确定，应尽一切努力评估并确保AF患者双心室起搏成功。