Levin D N, Hu X P, Tan K K, Galhotra S, Pelizzari C A, Chen G T, Beck R N, Chen C T, Cooper M D, Mullan J F
Department of Radiology, University of Chicago Hospitals, IL 60637.
Radiology. 1989 Sep;172(3):783-9. doi: 10.1148/radiology.172.3.2788893.
Three patients with intractable epilepsy, two with brain tumors, and one with encephalitis were imaged with magnetic resonance (MR) and positron emission tomography (PET). MR data were used to construct a three-dimensional (3D) computer model of the brain surface depicting the precentral (movement), postcentral (sensation), left inferior frontal (speech), and left superior temporal (hearing) gyri. PET-derived measurements of average surface metabolism were encoded as colors and mapped onto the 3D model by means of a retrospective technique for registering the two scans. The integrated 3D model depicted the location of PET-detected metabolic abnormalities with respect to the gyral anatomy visualized with MR. In each case, the predicted relationships were confirmed intraoperatively by means of inspection of the brain and electroencephalography. Multimodality 3D displays are likely to be particularly valuable for interpreting PET studies of epileptic patients and others with normal MR anatomy.
对三名难治性癫痫患者、两名脑肿瘤患者和一名脑炎患者进行了磁共振（MR）成像和正电子发射断层扫描（PET）。利用MR数据构建了大脑表面的三维（3D）计算机模型，描绘了中央前回（运动）、中央后回（感觉）、左侧额下回（言语）和左侧颞上回（听觉）。PET得出的平均表面代谢测量值被编码为颜色，并通过一种用于配准两次扫描的回顾性技术映射到3D模型上。整合后的3D模型描绘了PET检测到的代谢异常相对于通过MR可视化的脑回解剖结构的位置。在每种情况下，术中通过检查大脑和脑电图证实了预测的关系。多模态3D显示对于解释癫痫患者和其他MR解剖结构正常者的PET研究可能特别有价值。
