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ApoB is superior to LDL-C or non-HDL-C as a lipid marker for predicting the presence and severity of atherosclerosis in female patients with myocardial infarction.

作者信息

Zhang Hui-Wen, Zhao Xi, Zhang Yan, Li Sha, Zhu Cheng-Gang, Guo Yuan-Lin, Wu Na-Qiong, Gao Ying, Qing Ping, Sun Jing, Liu Geng, Dong Qian, Li Jian-Jun

机构信息

Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No 167 BeiLiShi Road, XiCheng District, Beijing, 100037, China.

Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No 167 BeiLiShi Road, XiCheng District, Beijing, 100037, China.

出版信息

Hellenic J Cardiol. 2017 May-Jun;58(3):223-225. doi: 10.1016/j.hjc.2016.11.032. Epub 2016 Nov 24.

DOI:10.1016/j.hjc.2016.11.032
PMID:27890629
Abstract
摘要

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1
ApoB is superior to LDL-C or non-HDL-C as a lipid marker for predicting the presence and severity of atherosclerosis in female patients with myocardial infarction.载脂蛋白B作为一种脂质标志物，在预测女性心肌梗死患者动脉粥样硬化的存在和严重程度方面优于低密度脂蛋白胆固醇或非高密度脂蛋白胆固醇。
Hellenic J Cardiol. 2017 May-Jun;58(3):223-225. doi: 10.1016/j.hjc.2016.11.032. Epub 2016 Nov 24.
2
Apolipoprotein B and Non-HDL Cholesterol Better Reflect Residual Risk Than LDL Cholesterol in Statin-Treated Patients.在接受他汀类药物治疗的患者中，载脂蛋白B和非高密度脂蛋白胆固醇比低密度脂蛋白胆固醇更能反映残余风险。
J Am Coll Cardiol. 2021 Mar 23;77(11):1439-1450. doi: 10.1016/j.jacc.2021.01.027.
3
High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study.高载脂蛋白B、低载脂蛋白A-I与致命性心肌梗死预测的改善（AMORIS研究）：一项前瞻性研究
Lancet. 2001 Dec 15;358(9298):2026-33. doi: 10.1016/S0140-6736(01)07098-2.
4
The apoB/apoA-I ratio is better than the cholesterol ratios to estimate the balance between plasma proatherogenic and antiatherogenic lipoproteins and to predict coronary risk.载脂蛋白B/载脂蛋白A-I比值在评估血浆促动脉粥样硬化和抗动脉粥样硬化脂蛋白之间的平衡以及预测冠心病风险方面优于胆固醇比值。
Clin Chem Lab Med. 2004;42(12):1355-63. doi: 10.1515/CCLM.2004.254.
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Association Between Serum LDL-C and ApoB and SYNTAX Score in Patients With Stable Coronary Artery Disease.稳定型冠状动脉疾病患者血清低密度脂蛋白胆固醇和载脂蛋白B与SYNTAX评分之间的关联
Angiology. 2018 Sep;69(8):724-729. doi: 10.1177/0003319717748771. Epub 2018 Jan 8.
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Apolipoprotein B/apolipoprotein A1 ratio and non-high-density lipoprotein cholesterol. Predictive value for CHD severity and prognostic utility in CHD patients.载脂蛋白B/载脂蛋白A1比值与非高密度脂蛋白胆固醇。对冠心病严重程度的预测价值及在冠心病患者中的预后效用。
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Do apolipoproteins improve coronary risk prediction in subjects with metabolic syndrome? Insights from the North Italian Brianza cohort study.载脂蛋白能否改善代谢综合征患者的冠心病风险预测？来自意大利北部布里安扎队列研究的见解。
Atherosclerosis. 2014 Sep;236(1):175-81. doi: 10.1016/j.atherosclerosis.2014.06.029. Epub 2014 Jul 14.
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Apolipoproteins A-I and B-markers in coronary risk evaluation.载脂蛋白A-I和B标志物在冠心病风险评估中的作用
Rom J Intern Med. 2007;45(3):251-8.
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Apolipoprotein B versus LDL-cholesterol: Association with other risk factors for atherosclerosis.载脂蛋白B与低密度脂蛋白胆固醇：与动脉粥样硬化其他危险因素的关联。
Clin Biochem. 2009 Aug;42(12):1246-51. doi: 10.1016/j.clinbiochem.2009.05.004. Epub 2009 May 18.
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Apolipoprotein B (apoB) more closely related to subclinical atherosclerosis than non-HDL cholesterol and LDL cholesterol.载脂蛋白B（apoB）比非高密度脂蛋白胆固醇和低密度脂蛋白胆固醇与亚临床动脉粥样硬化的关系更为密切。
J Intern Med. 2010 Dec;268(6):549-51. doi: 10.1111/j.1365-2796.2010.02286.x.

引用本文的文献

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Circulating serum fatty acid synthase is elevated in patients with diabetes and carotid artery stenosis and is LDL-associated.循环血清脂肪酸合酶在糖尿病和颈动脉狭窄患者中升高，并与 LDL 相关。
Atherosclerosis. 2019 Aug;287:38-45. doi: 10.1016/j.atherosclerosis.2019.05.016. Epub 2019 May 30.
2
Apolipoprotein B is associated with carotid atherosclerosis progression independent of individual cholesterol measures in a 9-year prospective study of Multi-Ethnic Study of Atherosclerosis participants.载脂蛋白 B 与颈动脉粥样硬化进展相关，独立于多民族动脉粥样硬化研究参与者 9 年前瞻性研究中的个体胆固醇测量值。
J Clin Lipidol. 2017 Sep-Oct;11(5):1181-1191.e1. doi: 10.1016/j.jacl.2017.07.001. Epub 2017 Jul 12.