Kutiyal Aditya Singh, Daga Mradul Kumar
Senior Resident, Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital , New Delhi, India .
Director Professor, Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital , New Delhi, India .
J Clin Diagn Res. 2016 Oct;10(10):OD14-OD15. doi: 10.7860/JCDR/2016/21220.8754. Epub 2016 Oct 1.
Ruptured Sinus of Valsalva (RSOV) is a rarely seen disease condition. RSOV can have varied presentations from being asymptomatic with just a cardiac murmur to profound hypotension. There has been simultaneous occurrence of RSOV with Infective Endocarditis (IE) in literature. Glomerulonephritis has also been reported in approximately 20% patients with IE. Large amount of proteinuria or decline in kidney functions is rarely encountered and mostly this finding has been incidental on routine evaluation. The co-existence of all the three conditions in a single patient is rare. This case was diagnosed to have RSOV with IE and was also diagnosed with post-infectious glomerulonephritis on renal biopsy. Patient was advised corrective cardiac surgery, but due to financial constraints, patient could not be operated and he died. Here, we report for the first time an unusual presence of both RSOV and sub-aortic membrane with IE complicated by glomerulonephritis.
瓦氏窦破裂（RSOV）是一种罕见的疾病状态。RSOV的表现多样，从仅伴有心脏杂音的无症状状态到严重低血压。文献中曾有RSOV与感染性心内膜炎（IE）同时出现的情况。约20%的IE患者也有肾小球肾炎的报道。大量蛋白尿或肾功能下降很少见，且大多是在常规评估中偶然发现。单一患者同时存在这三种情况很罕见。该病例经诊断患有RSOV合并IE，肾活检还诊断为感染后肾小球肾炎。患者被告知需进行心脏矫正手术，但由于经济限制，患者无法接受手术，最终死亡。在此，我们首次报告了RSOV和主动脉瓣下隔膜同时出现且合并IE并伴有肾小球肾炎的罕见情况。
