Touitou Y, Lecomte P, Auzéby A, Bogdan A, Besnier Y
Faculté de Médecine Pitié-Salpêtrière, Service de Biochimie Médicale, Paris, France.
Horm Metab Res. 1989 May;21(5):272-4. doi: 10.1055/s-2007-1009210.
We explored a 61 year old woman with mild hirsutism. An adrenal tumor was found in the left adrenal, which was held responsible for the androgen secretion. The in vitro incubation of the tumor tissue showed an impaired 11 beta-hydroxylation of 11-deoxycortisol. This is a rare and unusual case of adrenal pathology showing that a deficiency in 11 beta-hydroxylase activity does not rule out the presence of an adrenocortical adenoma.
我们对一名患有轻度多毛症的61岁女性进行了检查。在左肾上腺发现了一个肾上腺肿瘤，该肿瘤被认为是雄激素分泌的原因。肿瘤组织的体外培养显示11 - 脱氧皮质醇的11β - 羟化受损。这是一例罕见且不寻常的肾上腺病理病例，表明11β - 羟化酶活性缺乏并不排除肾上腺皮质腺瘤的存在。
